{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:09:51Z","timestamp":1777399791959,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1994,5,1]],"date-time":"1994-05-01T00:00:00Z","timestamp":767750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1994,5]]},"abstract":"<jats:p>\n                    The effect of changing a rate-responsive pacemaker program (which reacts to evoked QT interval) to fixed-rate ventricular pacing was studied in 10 patients with sick sinus syndrome (SSS). After the patients had been in the rate-responsive mode (VVIR) for at least one year, the exercise capacity (maximal oxygen consumption [peak VO\n                    <jats:sub>2<\/jats:sub>\n                    ], anaerobic threshold [AT], and cardiac output [CO] at these points) was examined. Three hours later on the same day, the pacemaker was reprogrammed to the fixed-rate pacing (WI) and the exercise capacity was examined again (VVI-S). One month later, a similar exercise test was also done in the VVI mode (VVI-L). There was no significant difference in peak VO\n                    <jats:sub>2<\/jats:sub>\n                    and AT between VVIR and VVI-S, but both peak VO\n                    <jats:sub>2<\/jats:sub>\n                    and AT were significantly lower in VVI-L than in WIR. However, there were no significant differences in the CO at peak VO\n                    <jats:sub>2<\/jats:sub>\n                    or AT between any of the pacing modes. These findings indicate that a WIR pacemaker should not be reprogrammed to the VVI mode in SSS patients, because the change can cause the exercise capacity to deteriorate.\n                  <\/jats:p>","DOI":"10.1177\/000331979404500504","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"353-360","source":"Crossref","is-referenced-by-count":1,"title":["Benefits of Rate-Responsive Pacing in Patients with Sick Sinus Syndrome"],"prefix":"10.1177","volume":"45","author":[{"given":"Masami","family":"Nishino","sequence":"first","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwa","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiko","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Kuryu","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Tanahashi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Osaka Rosai Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.280.6208.139"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a061236"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(86)90142-0"},{"key":"atypb4","first-page":"409","volume":"10","author":"Rosado L.","year":"1987","journal-title":"PACE"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)91947-6"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.50.2.112"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a061940"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1983.tb05301.x"},{"key":"atypb9","volume-title":"Fourth European Symposium on Cardiac Pacing. Abstract 132","author":"Show DB"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1981.50.1.217"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1990.68.6.2521"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.78.4.1060"},{"key":"atypb13","first-page":"219","volume":"112","author":"Wasserman K.","year":"1975","journal-title":"Am Rev Respir Dis"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1159\/000470528"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1990.tb02091.x"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1992.tb05138.x"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.58.6.613"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.1.184"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331979404500504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331979404500504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:15:47Z","timestamp":1777371347000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331979404500504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,5]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1994,5]]}},"alternative-id":["10.1177\/000331979404500504"],"URL":"https:\/\/doi.org\/10.1177\/000331979404500504","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,5]]}}}