{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:59:41Z","timestamp":1777399181984,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1998,7]]},"abstract":"<jats:p>Six normal subjects and 12 patients with clinical angina and significant ST depressions during baseline ambulatory cardiac monitoring were given a single treatment with the end-diastolic pneumatic compression boot, the Circulator Boot\u2122. With the use of contin uous electrical impedance measurements, multiple hemodynamic variables were followed in five situations: (1) baseline before pumping; during end-diastolic pumping (2) on both legs after every heartbeat, (3) on one leg after every heartbeat, and (4) on both legs on alternate beats; and (5) during pumping on both legs during every systole. Both an increase in venous return and a reduction in afterload likely contributed to significant increases in cardiac output (CO) (51.1 \u00b1 33.6%), stroke volume (SV) (52.1 \u00b1 35.6%), change in impedance over time (dZ\/dT) (72.0 \u00b1 68.1%), cardiac index (CI) (51.2 \u00b1 33.8%), and acceleration index (50.7 \u00b1 62.2%) during end-diastolic pumping on both legs after every heartbeat. A crucial role for afterload reduction was implied by opposite effects observed on CO, CI, dZ\/dT, and SV during systolic pumping. Again, reductions (or a lack of an increase) in ventricular ejection time and\/or the preejection period suggested a decrease in afterload during end-diastolic pumping. Pumping on one leg after every beat and on both legs on alternate beats was also effective but less so. After the initial study, the patients were given 14 additional end-diastolic treatments to both legs over 3 weeks. A clinical benefit for the patients was shown by symptomatic improvement in all patients along with a significant reduction in the amount and duration of the RST abnor malities in their ambulatory heart monitoring (p = 0.012).<\/jats:p>","DOI":"10.1177\/000331979804900702","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"523-535","source":"Crossref","is-referenced-by-count":2,"title":["Improved Hemodynamics Shown by Continuous Monitoring of Electrical Impedance During External Counterpulsation with the End-Diastolic Pneumatic Boot and Improved Ambulatory EKG Monitoring After 3 Weeks of Therapy"],"prefix":"10.1177","volume":"49","author":[{"given":"Richard S.","family":"Dillon","sequence":"first","affiliation":[{"name":"Bryn Mawr Medical Building North 828 Old Lancaster Road Bryn Mawr, PA 19010"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1998,7,1]]},"reference":[{"key":"atypb1","first-page":"338","volume":"166","author":"Guyton DP","year":"1988","journal-title":"Surg Gynecol Obstet"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(88)80418-5"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1038\/327524a0"},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1177\/0003319797048005S03","volume":"48","author":"Dillon RS","year":"1997","journal-title":"Angiology"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/0003319797048005S04"},{"key":"atypb6","first-page":"203","volume":"29","author":"Wang X.","year":"1995","journal-title":"Biomed Instrum Technol"},{"key":"atypb7","first-page":"56","author":"Bucher N.","year":"1992","journal-title":"RN"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199412000-00004"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.1996.tb03489.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90727-G"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80427-5"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1177\/000331979604700203"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)91349-5"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8651(18)30593-9"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90298-0"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.2.762"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199601113340201"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.2307\/1268974"},{"key":"atypb19","unstructured":"Barnes RW: Noninvasive diagnostic techniques in peripheral vascular disease. 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