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A protein data bank search showed that this sequence corresponded to residues 41 to 60 of human Raf-1 protein. Sera from 16 of 27 patients with Meniere's disease showed reactivity to the recombinant purified glutathione-S-transferase\u2013Raf-1 protein. These results support the hypothesis that a subgroup of patients who suffer from Meniere's disease, as well as some other kinds of autoimmune inner ear diseases, have an autoantibody against Raf-1 protein.<\/jats:p>","DOI":"10.1177\/000348940010901201","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:40:52Z","timestamp":1412347252000},"page":"1093-1098","source":"Crossref","is-referenced-by-count":13,"title":["Proto-Oncogene Raf-1 as an Autoantigen in Meniere's Disease"],"prefix":"10.1177","volume":"109","author":[{"given":"Kuang-Chuan","family":"Cheng","sequence":"first","affiliation":[{"name":"Raritan, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsuoka","sequence":"additional","affiliation":[{"name":"Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung Mi","family":"Lee","sequence":"additional","affiliation":[{"name":"Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Seog","family":"Kwon","sequence":"additional","affiliation":[{"name":"Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nacksung","family":"Kim","sequence":"additional","affiliation":[{"name":"New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimilliano","family":"Mora","sequence":"additional","affiliation":[{"name":"Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc S.","family":"Krug","sequence":"additional","affiliation":[{"name":"Glen Mills, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. 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