{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:17:36Z","timestamp":1777421856228,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2000,12,1]],"date-time":"2000-12-01T00:00:00Z","timestamp":975628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2000,12]]},"abstract":"<jats:p>\n                    \u03b2-Trace protein is an immunological marker for the detection of cerebrospinal fluid traces. The aim of the study was to evaluate the predictive value of the \u03b2-trace protein test. We investigated 145 specimens for cerebrospinal fluid using \u03b2-trace protein. All case notes were retrospectively reviewed and tabulated for indication and procedure with focus on outcome. The specimens were analyzed by Immunoelectrophoresis. \u03b2-Trace protein was detected in 62 specimens and was absent in 83. In correlation with the clinical course, the clinical findings, the results of high-resolution computed tomography of the paranasal sinuses or petrous bone, computed tomographic cisternography, magnetic resonance imaging, indium 111\u2013pentetic acid radionuclide cisternography, intraoperative findings, and visualization using sodium-fluorescein, there were no false-positive results. In 6 cases, a false-negative result occurred. The overall accuracy was 95.68%. The \u03b2-trace test has a specificity of near 100% and a sensitivity of 91.17%. Analysis of \u03b2-trace protein is a valuable test and has some advantages in comparison with the \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -transferrin assay.\n                  <\/jats:p>","DOI":"10.1177\/000348940010901202","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:40:52Z","timestamp":1412347252000},"page":"1099-1102","source":"Crossref","is-referenced-by-count":43,"title":["Clinical Experience with Beta-Trace Protein as a Marker for Cerebrospinal Fluid"],"prefix":"10.1177","volume":"109","author":[{"given":"Gregor","family":"Bachmann","sequence":"first","affiliation":[{"name":"Marko Nekic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Michel","sequence":"additional","affiliation":[{"name":"Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,12,1]]},"reference":[{"key":"bibr1-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800401"},{"key":"bibr2-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.2297"},{"key":"bibr3-000348940010901202","first-page":"193","volume-title":"Intracranial and inner-ear physiology and pathophysiology","author":"Bachmann G","year":"1998"},{"key":"bibr4-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-19-06119.1996"},{"key":"bibr5-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1007\/BF01743251"},{"key":"bibr6-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0420149"},{"key":"bibr7-000348940010901202","first-page":"429","volume":"6","author":"Hayaishi O","year":"1993","journal-title":"J Lipid Mediat"},{"key":"bibr8-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1996.tb01737.x"},{"key":"bibr9-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-998807"},{"key":"bibr10-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-997485"},{"key":"bibr11-000348940010901202","first-page":"341","volume":"22","author":"Skedros DG","year":"1993","journal-title":"J Otolaryngol"},{"key":"bibr12-000348940010901202","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/42.12.1984"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348940010901202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348940010901202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:18:25Z","timestamp":1777375105000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348940010901202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2000,12]]}},"alternative-id":["10.1177\/000348940010901202"],"URL":"https:\/\/doi.org\/10.1177\/000348940010901202","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,12]]}}}