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We report a case in which a squamous cell carcinoma developed within a burn scar on the cheek and then a malignant melanoma arose within the burn scar after the squamous cell carcinoma had been excised. We also review the available literature on burn scar carcinoma, covering the demographics, pathogenesis, diagnosis, prognosis, and treatment of the disease. Given the multifocality of this disease process, we advocate aggressive resection of the entire burn scar, as well as the tumor, to prevent the development of further cancers within the wound.<\/jats:p>","DOI":"10.1177\/000348940111000414","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:40:52Z","timestamp":1412347252000},"page":"369-376","source":"Crossref","is-referenced-by-count":22,"title":["Malignant Melanoma Arising within a Burn Scar Case Report and Review of the Literature"],"prefix":"10.1177","volume":"110","author":[{"given":"Paul M.","family":"Spring","sequence":"first","affiliation":[{"name":"Lexington, Kentucky"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel K.","family":"El-Naggar","sequence":"additional","affiliation":[{"name":"Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey N.","family":"Myers","sequence":"additional","affiliation":[{"name":"Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard N.","family":"Langstein","sequence":"additional","affiliation":[{"name":"Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,4,1]]},"reference":[{"key":"bibr1-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30861-6"},{"key":"bibr2-000348940111000414","first-page":"749","volume":"51","author":"Treves N","year":"1930","journal-title":"Surg Gynecol Obstet"},{"key":"bibr3-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198404000-00009"},{"key":"bibr4-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198404000-00015"},{"key":"bibr5-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196508000-00021"},{"key":"bibr6-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1998.tb04207.x"},{"key":"bibr7-000348940111000414","first-page":"579","volume":"95","author":"Lawrence EA","year":"1952","journal-title":"Surg Gynecol Obstet"},{"key":"bibr8-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-197710000-00010"},{"key":"bibr9-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-199009000-00016"},{"key":"bibr10-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(41)90399-9"},{"key":"bibr11-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198805000-00014"},{"key":"bibr12-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-195810000-00008"},{"key":"bibr13-000348940111000414","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1989.01410010125024"},{"key":"bibr14-000348940111000414","unstructured":"Ewing J. 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