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The minor symptoms include fever, halitosis, fatigue, and dental pain. Microorganisms play a significant role in the persistence and origination of the inflammatory process, although the exact role of these organisms in the pathogenesis of chronic rhinosinusitis is unclear. The clinical diagnosis relies heavily on the patient history and physical examination, which may include nasal endoscopy and computed tomography. Diagnostic techniques are here reviewed.<\/jats:p>","DOI":"10.1177\/00034894041130s504","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T08:37:06Z","timestamp":1483691826000},"page":"10-14","source":"Crossref","is-referenced-by-count":31,"title":["Diagnosis of Chronic Rhinosinusitis"],"prefix":"10.1177","volume":"113","author":[{"given":"Donald C.","family":"Lanza","sequence":"first","affiliation":[{"name":"Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,5,1]]},"reference":[{"key":"bibr1-00034894041130S504","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770001-9"},{"key":"bibr2-00034894041130S504","doi-asserted-by":"publisher","DOI":"10.1177\/194589240201600102"},{"key":"bibr3-00034894041130S504","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980223295-7"},{"key":"bibr4-00034894041130S504","doi-asserted-by":"publisher","DOI":"10.1053\/hn.2003.v128.amhn0312811"},{"key":"bibr5-00034894041130S504","doi-asserted-by":"publisher","DOI":"10.1177\/194589240101500501"},{"key":"bibr6-00034894041130S504","unstructured":"Montgomery L, Lanza DC, Schwartz JS, Tanabodee J, Kennedy DW. 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