{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:23:40Z","timestamp":1777422220317,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"},{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>Vestibular schwannomas are benign neoplasms that arise from Schwann cells of the eighth cranial nerve. Most manifest clinically with tinnitus, unilateral sensorineural hearing loss, and disequilibrium secondary to compression of the vestibulocochlear nerve; major adverse events such as intratumoral hemorrhage causing acute neurologic deterioration are rare. We report the case of a 69-year-old man with a large vestibular schwannoma who required anticoagulation for several medical comorbidities. The patient began having progressively worsening neurologic symptoms, including facial nerve paralysis and dysequilibrium, which confined him to a wheelchair. After presentation, the patient was admitted to the hospital. Several days after alteration of his anticoagulation therapy in preparation for surgery, he developed intracranial hemorrhage. Attempts were made to stabilize the patient, including posterior fossa craniectomy and evacuation of hematoma; however, the intracranial hemorrhage ultimately resulted in a fatal outcome. During this procedure, a biopsy specimen was obtained, showing benign vestibular schwannoma. The literature for intratumoral hemorrhage into vestibular schwannoma and the pathologic findings in our case are reviewed.<\/jats:p>","DOI":"10.1177\/000348941011900607","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T05:05:16Z","timestamp":1496120716000},"page":"402-405","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Fatal Case of Tumor-Associated Hemorrhage in a Large Vestibular Schwannoma"],"prefix":"10.1177","volume":"119","author":[{"given":"Charles W.","family":"Yates","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, OSU Eye and Ear Institute, The Ohio State University, Columbus, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Ohio State University, Columbus, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Packer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, OSU Eye and Ear Institute, The Ohio State University, Columbus, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"Jacob","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, OSU Eye and Ear Institute, The Ohio State University, Columbus, Ohio."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,5,30]]},"reference":[{"key":"bibr1-000348941011900607","first-page":"706","volume":"21","author":"Odabasi A.O.","year":"2000","journal-title":"Am J Otol"},{"key":"bibr2-000348941011900607","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.30.972"},{"key":"bibr3-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-004-0039-x"},{"key":"bibr4-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000188339.45772.be"},{"key":"bibr5-000348941011900607","first-page":"236","volume":"18","author":"Glasscock M.E. I.I.I.","year":"1997","journal-title":"Am J Otol"},{"key":"bibr6-000348941011900607","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1974.41.3.0391"},{"key":"bibr7-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(87)90290-4"},{"key":"bibr8-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-006-1107-8"},{"key":"bibr9-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2003.01209.x"},{"key":"bibr10-000348941011900607","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(98)00002-X"},{"key":"bibr11-000348941011900607","doi-asserted-by":"publisher","DOI":"10.3171\/foc.1998.5.3.15"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941011900607","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941011900607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:19:25Z","timestamp":1777375165000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/000348941011900607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1177\/000348941011900607"],"URL":"https:\/\/doi.org\/10.1177\/000348941011900607","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}