{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:27:23Z","timestamp":1777422443988,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study evaluated the efficacy of concurrent superselective intra-arterial chemotherapy and radiotherapy without surgery for late-stage squamous cell carcinoma of the temporal bone, which typically has a poor prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The subjects were 5 patients treated at our hospital between 2007 and 2010 for primary cancer of the temporal bone. One patient had a stage T3 tumor, and 4 patients had T4 tumors, according to the Pittsburgh staging system. All patients received irradiation with a conventional once-daily fraction of 2 Gy, and the total dose ranged from 60 to 66 Gy. Intra-arterial cisplatin via transfemoral catheterization and intravenous sodium thiosulfate were administered. The contribution of each vessel in supplying blood to the primary tumor was determined by real-time computed tomographic angiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Three patients obtained a complete response. The same 3 patients remain alive without local recurrence (mean survival, 28 months), 1 patient died of distant metastasis without local recurrence after 19 months, and 1 patient remains alive with local recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Although the small number of patients prevents comparisons with other treatments, the present study obtained good results. This may become an effective treatment for patients with late-stage squamous cell carcinoma of the temporal bone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/000348941112000604","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:44:54Z","timestamp":1412347494000},"page":"372-376","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Concurrent Superselective Intra-Arterial Chemotherapy and Radiotherapy for Late-Stage Squamous Cell Carcinoma of the Temporal Bone"],"prefix":"10.1177","volume":"120","author":[{"given":"Hisashi","family":"Sugimoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyako","family":"Hatano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomokazu","family":"Yoshizaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,6,1]]},"reference":[{"key":"bibr1-000348941112000604","first-page":"582","volume":"21","author":"Moody SA","year":"2000","journal-title":"Am J Otol"},{"key":"bibr2-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900909"},{"key":"bibr3-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.11.012"},{"key":"bibr4-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790350017006"},{"key":"bibr5-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2006.00283.x"},{"key":"bibr6-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215109005143"},{"key":"bibr7-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.7.834"},{"key":"bibr8-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1177\/019459989411000303"},{"key":"bibr9-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2006.03.001"},{"key":"bibr10-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911800303"},{"key":"bibr11-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)80089-3"},{"key":"bibr12-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880140505"},{"key":"bibr13-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890200043010"},{"key":"bibr14-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100094172"},{"key":"bibr15-000348941112000604","first-page":"189","volume":"53","author":"Conley J","year":"1965","journal-title":"Trans Am Otol Soc"},{"key":"bibr16-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870101)59:1<156::AID-CNCR2820590130>3.0.CO;2-#"},{"key":"bibr17-000348941112000604","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1984.tb01511.x"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941112000604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941112000604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:20:09Z","timestamp":1777375209000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348941112000604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1177\/000348941112000604"],"URL":"https:\/\/doi.org\/10.1177\/000348941112000604","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}