{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:18:26Z","timestamp":1793092706956,"version":"4.5.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Currently, botulinum toxin (Botox) injection is the standard of treatment for adductor spasmodic dysphonia (ADSD). We sought to compare the outcome of selective laryngeal adductor denervation-reinnervation (SLAD-R) surgery for ADSD to that of Botox injections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patient-oriented measures (VHI-10) and objective single-blinded gradings of digital voice recordings were utilized as outcome measures. The surgical cohort, recruited by retrospective patient selection, consisted of 77 patients with a mean follow-up time of 7.54 \u00b1 2.55 years (range, 2.2 to 14.2 years). The injection cohort, recruited prospectively, included 28 patients with a mean follow-up time of 46.37 \u00b1 5.51 days (range, 36 to 54 days).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>As measured by the VHI-10, the surgical patients had significantly improved voice handicap outcome scores (mean, 14.4 \u00b1 13.6) as compared to the patients who had Botox injection (mean, 26.5 \u00b1 12.1; p = 0.001). Aside from VHI-10 item 2, the surgical group demonstrated significantly improved voice-related function on each VHI-10 component (p = 0.01). Within the injection subgroup, 88% agreed that Botox successfully treats their ADSD, yet only 63% agreed that Botox improves their speech consistently. Within the surgical subgroup, 82% would recommend this surgery to others, and 78% agreed that their voice was actually better after surgery than after Botox. Objective voice ratings demonstrated similar levels of breathiness and overall voice quality in the treatment subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>When indicated, the SLAD-R surgery for ADSD demonstrates outcomes equal to or superior to those of the current standard of Botox injections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/000348941212100408","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:44:54Z","timestamp":1412347494000},"page":"231-238","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":29,"title":["Surgery or Botulinum Toxin for Adductor Spasmodic Dysphonia: A Comparative Study"],"prefix":"10.1177","volume":"121","author":[{"given":"Abie H.","family":"Mendelsohn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald S.","family":"Berke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,4,1]]},"reference":[{"key":"bibr1-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.4.389"},{"key":"bibr2-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.05.624"},{"key":"bibr3-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80211-5"},{"key":"bibr4-000348941212100408","author":"Silverman EP","year":"2011","journal-title":"J Voice"},{"key":"bibr5-000348941212100408","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1288\/00005537-199106000-00010","volume":"101","author":"Troung DD","year":"1991","journal-title":"Laryngoscope"},{"key":"bibr6-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199810000-00003"},{"key":"bibr7-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21395"},{"key":"bibr8-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31815e8be0"},{"key":"bibr9-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1177\/000348940311200403"},{"key":"bibr10-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200409000-00019"},{"key":"bibr11-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800302"},{"key":"bibr12-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000403"},{"key":"bibr13-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000201990.97955.E4"},{"key":"bibr14-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80252-8"},{"key":"bibr15-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210101101"},{"key":"bibr16-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200409000-00009"},{"key":"bibr17-000348941212100408","author":"Morzaria S","year":"2010","journal-title":"J Voice"},{"key":"bibr18-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1044\/1092-4388(2005\/005)"},{"key":"bibr19-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.12.1393"},{"key":"bibr20-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.03047.x"},{"key":"bibr21-000348941212100408","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1002\/lary.20855","volume":"120","author":"Venkatesan NN","year":"2010","journal-title":"Laryngoscope"},{"key":"bibr22-000348941212100408","doi-asserted-by":"publisher","DOI":"10.1177\/000348940811700301"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941212100408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941212100408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:20:18Z","timestamp":1777375218000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348941212100408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1177\/000348941212100408"],"URL":"https:\/\/doi.org\/10.1177\/000348941212100408","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}