{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:30:50Z","timestamp":1777422650238,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Myospherulosis is a foreign body reaction induced by the application of oil-based ointments. Myospherulosis in the ear is extremely rare. Only 4 cases have been described, all of which occurred after (repeated) mastoid surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We present a case of persistent otorrhea and conductive hearing loss caused by myospherulosis in the middle ear following tympanoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The patient underwent revision middle ear surgery with removal of abnormally thick, pale tissue in the middle ear. Histology showed a foreign body reaction with signs of myospherulosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Myospherulosis is a very rare complication of the use of oil-based ointments. Surgeons should be aware that these products might cause a foreign body reaction leading to myospherulosis. In patients who have chronic otorrhea after previous mastoid or middle ear surgery, myospherulosis should be considered in the differential diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/000348941312200709","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T04:25:06Z","timestamp":1484281506000},"page":"461-463","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Chronic Otorrhea Caused by Myospherulosis in the Middle Ear after Tympanoplasty"],"prefix":"10.1177","volume":"122","author":[{"given":"Jimmie","family":"Honings","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick F. M.","family":"Dammeijer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,7,1]]},"reference":[{"key":"bibr1-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/51.6.699"},{"key":"bibr2-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/67.2.118"},{"key":"bibr3-000348941312200709","first-page":"33","volume":"87","author":"De Schryver-Kecskemeti K","year":"1977","journal-title":"Am J Pathol"},{"key":"bibr4-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(12)80127-1"},{"key":"bibr5-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1007\/BF00178475"},{"key":"bibr6-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1258\/002221503321892389"},{"key":"bibr7-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2009.01.002"},{"key":"bibr8-000348941312200709","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-814448"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941312200709","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348941312200709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:21:04Z","timestamp":1777375264000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348941312200709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1177\/000348941312200709"],"URL":"https:\/\/doi.org\/10.1177\/000348941312200709","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}