{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:32:27Z","timestamp":1777426347555,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T00:00:00Z","timestamp":1461628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Cholesteatomas can grow to a remarkable size before clinically making their presence felt. Managing giant cholesteatomas and their complications can become a challenge for the otological surgeon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We describe a case of a giant congenital cholesteatoma of the mastoid in an adult. The lesion extended to the sigmoid sinus, jugular bulb, carotid canal, occipital condyle, and the lateral portion of the first cervical vertebra. Surgical excision was performed using a combined microscopic and endoscopic surgical approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Our combined surgical technique enabled a more accurate removal of the cholesteatoma than a microscopic approach alone, with no surgical complications or damage to the structures affected by the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Using endoscopic instruments to manage giant cholesteatomas can help to avoid complications and improve surgical radicality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489416646118","type":"journal-article","created":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T23:35:01Z","timestamp":1461713701000},"page":"687-693","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Combined Surgical Approach to Giant Cholesteatoma"],"prefix":"10.1177","volume":"125","author":[{"given":"Diego","family":"Cazzador","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Otolaryngology Section, University of Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niccol\u00f2","family":"Favaretto","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Otolaryngology Section, University of Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Zanoletti","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Otolaryngology Section, University of Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Martini","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Otolaryngology Section, University of Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,4,26]]},"reference":[{"key":"bibr1-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000136875.41630.d6"},{"key":"bibr2-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1086054"},{"issue":"5","key":"bibr3-0003489416646118","first-page":"281","volume":"32","author":"Zanoletti E","year":"2012","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"bibr4-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1177\/000348941112001102"},{"key":"bibr5-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.9.1009"},{"key":"bibr6-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31369-4"},{"key":"bibr7-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.107318"},{"issue":"2","key":"bibr8-0003489416646118","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0001-6519(01)78190-3","volume":"52","author":"Rodriguez Verdugo M","year":"2001","journal-title":"Acta Otorrinolaringol Esp"},{"key":"bibr9-0003489416646118","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2004.02082"},{"key":"bibr10-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1177\/0194599810391850"},{"key":"bibr11-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1376200"},{"key":"bibr12-0003489416646118","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2010.543430"},{"key":"bibr13-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2013.05.023"},{"issue":"3","key":"bibr14-0003489416646118","first-page":"184","volume":"34","author":"Zanoletti E","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"bibr15-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e328364b457"},{"issue":"2","key":"bibr16-0003489416646118","first-page":"168","volume":"15","author":"Rosenberg SI","year":"1994","journal-title":"Am J Otol"},{"issue":"4","key":"bibr17-0003489416646118","first-page":"481","volume":"37","author":"Presutti L","year":"2008","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"bibr18-0003489416646118","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182096b39"},{"issue":"6","key":"bibr19-0003489416646118","first-page":"427","volume":"34","author":"Presutti L","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"}],"container-title":["Annals of Otology, Rhinology &amp; 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