{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T11:01:33Z","timestamp":1793790093002,"version":"4.6.1"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,3,18]],"date-time":"2017-03-18T00:00:00Z","timestamp":1489795200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Herpes simplex virus (HSV) laryngitis is rare in adults. We add a case report to the literature and perform a literature review to further delineate the clinical presentation, course, and treatment of HSV laryngitis in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Case report and literature review using PubMed and Ovid databases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Ten cases of diagnosed HSV laryngitis in adults were reported in the literature. It is more common in immunocompromised patients. The mean patient age was 51 years with a male to female ratio of 1:1. The clinical presentation and course of HSV laryngitis is variable. Patients may have mild chronic symptoms, such as dysphonia, or a fulminant course with rapid airway compromise. On laryngoscopic exam, the most common findings are a white exudate or ulceration. The most common treatment is with antiviral medication, such as acyclovir, which tends to be highly effective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Herpes simplex virus laryngitis is rare. Clinical presentation of HSV laryngitis is variable, and its course may be indolent or fulminant. Treatment with antiviral medication tends to be highly effective.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489417699421","type":"journal-article","created":{"date-parts":[[2017,3,18]],"date-time":"2017-03-18T09:02:33Z","timestamp":1489827753000},"page":"424-428","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Herpes Simplex Virus Laryngitis Presenting as Airway Obstruction: A Case Report and Literature Review"],"prefix":"10.1177","volume":"126","author":[{"given":"Lucas","family":"Harless","sequence":"first","affiliation":[{"name":"Kaiser Permanente Oakland Medical Center Department of Head and Neck Surgery, Oakland, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Jiang","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Oakland Medical Center Department of Head and Neck Surgery, Oakland, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Schneider","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Oakland Medical Center Department of Pathology, Oakland, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Durr","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Oakland Medical Center Department of Head and Neck Surgery, Oakland, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,3,18]]},"reference":[{"key":"bibr1-0003489417699421","unstructured":"Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. Herpesvirus Infections. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. eds. Harrison\u2019s Manual of Medicine, 18e. New York, NY: McGraw-Hill; 2013. http:\/\/accessmedicine.mhmedical.com\/content.aspx?bookid=1140&Sectionid=63500922. Accessed April 30, 2016."},{"key":"bibr2-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511500136X"},{"key":"bibr3-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.2.382"},{"key":"bibr4-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2012.11.006"},{"key":"bibr5-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25555"},{"key":"bibr6-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1177\/000348949410300912"},{"key":"bibr7-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.5.672"},{"key":"bibr8-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1177\/014556130908800203"},{"key":"bibr9-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(99)90010-5"},{"key":"bibr10-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-007928"},{"key":"bibr11-0003489417699421","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900616"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0003489417699421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0003489417699421","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0003489417699421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:31:35Z","timestamp":1777375895000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0003489417699421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,18]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1177\/0003489417699421"],"URL":"https:\/\/doi.org\/10.1177\/0003489417699421","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,18]]}}}