{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:40:55Z","timestamp":1787665255694,"version":"build-2736575974"},"reference-count":31,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T00:00:00Z","timestamp":1539993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>We aimed to restore dose-volume parameters of swallowing-related structures (SRSs) by evaluating long-term swallowing dysfunctions after radiotherapy (RT) in head and neck cancer patients (HNCPs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Head and neck cancer patients whose pharyngeal region was involved in RT portal and treated with definitive RT\/chemoradiotherapy (CRT) were included in the analyses. Patients underwent objective swallowing assessment by flexible endoscopic evaluation of swallowing (FEES). Volumes of SRSs that received 55 Gy (V\n                      <jats:sub>55<\/jats:sub>\n                      ) (mean dose [D\n                      <jats:sub>mean<\/jats:sub>\n                      ]) were evaluated according to the dose-volume histograms of each patient. For every SRS, optimal dose-volume cut-off values were determined by receiver operating characteristic curve analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty-five patients at a median 20 months (range, 12-26 months) after their treatments were evaluated. There was a strong negative correlation between FEES scores and dose-volume parameters of SRS ( r \u2a7d \u20130.5, P &lt; .0001). According to our results, middle pharyngeal constrictor (MPC) and inferior pharyngeal constrictor (IPC) had a D\n                      <jats:sub>mean<\/jats:sub>\n                      &gt; 57 Gy, base of tongue (BOT) D\n                      <jats:sub>mean<\/jats:sub>\n                      &gt; 50 Gy, supraglottic larynx (SGL) and glottic larynx (GL) D\n                      <jats:sub>mean<\/jats:sub>\n                      &gt; 55 Gy, and cervical esophagus (CE) D\n                      <jats:sub>mean<\/jats:sub>\n                      &gt; 45 Gy. MPC V\n                      <jats:sub>55<\/jats:sub>\n                      &gt; 70%, IPC V\n                      <jats:sub>55<\/jats:sub>\n                      &gt; 50%, BOT V\n                      <jats:sub>55<\/jats:sub>\n                      &gt; 65%, CE V\n                      <jats:sub>55<\/jats:sub>\n                      &gt; 40%, and SGL and GL V\n                      <jats:sub>55<\/jats:sub>\n                      &gt; 50% were significant predictors for dysphagia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>It was found that dysphagia correlates strongly with dose-volume parameters of SRSs. IPC, SGL, and CE were found to be structures significantly associated with dysphagia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489418804260","type":"journal-article","created":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T04:55:26Z","timestamp":1540011326000},"page":"73-84","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Radiation-Associated Chronic Dysphagia Assessment by Flexible Endoscopic Evaluation of Swallowing (FEES) in Head and Neck Cancer Patients: Swallowing-Related Structures and Radiation Dose-Volume Effect"],"prefix":"10.1177","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9733-774X","authenticated-orcid":false,"given":"Ozlem","family":"Ozkaya Akagunduz","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Radiation Oncology, Ege University, Ankara Street, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibel","family":"Eyigor","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Physical Therapy and Rehabilitation, Ege University, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Kirakli","sequence":"additional","affiliation":[{"name":"Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Radiation Oncology Department, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emin","family":"Tavlayan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Radiation Oncology, Ege University, Ankara Street, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep","family":"Erdogan Cetin","sequence":"additional","affiliation":[{"name":"Ardahan State Hospital, Department of Otorhinolaryngology, Ardahan, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulsen","family":"Kara","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Radiation Oncology, Ege University, Ankara Street, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Esassolak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Radiation Oncology, Ege University, Ankara Street, Izmir, 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