{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T01:07:25Z","timestamp":1781140045805,"version":"3.54.1"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T00:00:00Z","timestamp":1545004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Laryngopharyngeal herpes simplex virus infection is rare and presents typically in the supraglottis. Findings on presentation can range from small mucosal lesions to fungating obstructive masses mimicking neoplasm. Laryngopharyngeal herpes is a medically treated disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Identify potential treatment in cases that are refractory to antiviral medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Individual case with treatment adapted from other case report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We report a case of bulky, obstructive supraglottic and glottic herpes virus laryngitis that presented with dysphonia, dysphagia, and airway complaints resistant to acyclovir analogues that was treated effectively with intralesional cidofovir injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our promising initial response suggests a potential novel treatment for this unusual condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489418818579","type":"journal-article","created":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T06:55:49Z","timestamp":1545029749000},"page":"267-270","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass"],"prefix":"10.1177","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8673-0327","authenticated-orcid":false,"given":"Charles Q.","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Walter Reed National Military Medical Center, Bethesda, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anisha","family":"Mathur","sequence":"additional","affiliation":[{"name":"Departmant of Infectious Disease, Medstar Georgetown University Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Princy N.","family":"Kumar","sequence":"additional","affiliation":[{"name":"Departmant of Infectious Disease, Medstar Georgetown University Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaninder K.","family":"Dhillon","sequence":"additional","affiliation":[{"name":"Johns Hopkins Otolaryngology-Laryngology Division, Bethesda, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,12,17]]},"reference":[{"key":"bibr1-0003489418818579","doi-asserted-by":"publisher","DOI":"10.2217\/fvl.15.85"},{"key":"bibr2-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00131-5"},{"issue":"2","key":"bibr3-0003489418818579","first-page":"51","volume":"32","author":"Ottria L","year":"2018","journal-title":"J Biol Regul Homeost Agents"},{"key":"bibr4-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25555"},{"key":"bibr5-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.363"},{"key":"bibr6-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2018.e00443"},{"key":"bibr7-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1177\/0003489417699421"},{"key":"bibr8-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511500136X"},{"issue":"3","key":"bibr9-0003489418818579","first-page":"1","volume":"64","author":"Centers for Disease Control and Prevention","year":"2015","journal-title":"MMWR Recomm Rep"},{"issue":"12","key":"bibr10-0003489418818579","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1177\/106002809703101213","volume":"31","author":"Martinez CM","year":"1997","journal-title":"Ann Pharmacother"},{"key":"bibr11-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.5.497"},{"key":"bibr12-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2008.05.013"},{"key":"bibr13-0003489418818579","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2005.00099.x"},{"key":"bibr14-0003489418818579","author":"Nieto Rodr\u00edguez D","year":"2017","journal-title":"Actas Dermosifiliogr"}],"container-title":["Annals of Otology, Rhinology &amp; 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