{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:39:01Z","timestamp":1777426741141,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T00:00:00Z","timestamp":1550534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To identify and characterize hearing loss (HL) in children with septo-optic dysplasia (SOD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Otologic and audiometric data for patients less than 18 years of age identified as having SOD who were seen in the Children\u2019s Healthcare of Atlanta-Scottish Rite Hospital clinic between 2013 and 2017 were collected and reviewed through a HIPAA-compliant medical record search. Relevant literature was also reviewed with the assistance of Medline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Sixty-four patients with SOD were identified, and 7 of those patients (10.9%) were diagnosed with hearing loss. Type of hearing loss was sensorineural (SNHL) in 5 patients (63%), mixed (MHL) in 1(14%), and conductive (CHL) in 1(14%). Bilateral loss presented in 60% (3\/5) of SNHL patients, while the rest demonstrated unilateral loss. Unilateral findings included cochlear nerve deficiency (1) and atresia\/microtia (1). Tympanostomy tubes were required in 57% (4\/7) of SOD children with hearing loss. Amplification was successfully implemented in 86% (6\/7).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Hearing loss was found in nearly 11% of SOD children, and SNHL was identified as (63%) the predominant form of loss. To our knowledge, this is the first retrospective review of hearing loss in a pediatric SOD cohort and the first to report of cochlear nerve deficiency and atresia\/microtia in this population. Based on these findings, early identification of hearing loss with imaging when appropriate and treatment of otitis in this population is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489419832629","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T14:54:49Z","timestamp":1550674489000},"page":"485-489","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hearing Loss in Pediatric Septo-Optic Dysplasia"],"prefix":"10.1177","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2247-4330","authenticated-orcid":false,"given":"Brian William","family":"Herrmann","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital Colorado, Aurora, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Campbell R.","family":"Hathaway","sequence":"additional","affiliation":[{"name":"School of Medicine Greenville Campus, University of South Carolina, Greenville, South Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Fadell","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital Colorado, Aurora, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,19]]},"reference":[{"key":"bibr1-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2009.125"},{"key":"bibr2-0003489419832629","first-page":"61","volume":"69","author":"Reeves D.","year":"1941","journal-title":"Bull Johns Hopkins Hosp"},{"key":"bibr3-0003489419832629","first-page":"267","volume":"77","author":"De Morsier G","year":"1956","journal-title":"Schweizer Arch Neurol Psychiatr"},{"key":"bibr4-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.07.031"},{"key":"bibr5-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-009596"},{"key":"bibr6-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1093\/pch\/16.5.301"},{"key":"bibr7-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-017-0164-8"},{"key":"bibr8-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1159\/000433468"},{"key":"bibr9-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30803"},{"key":"bibr10-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030527"},{"key":"bibr11-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1177\/197140091302600111"},{"key":"bibr12-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.868"},{"key":"bibr13-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1016\/j.modgep.2007.05.002"},{"key":"bibr14-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1609"},{"key":"bibr15-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970331)69:3<235::AID-AJMG4>3.0.CO;2-K"},{"key":"bibr16-0003489419832629","first-page":"e15","volume":"6","author":"Garvin J","year":"2016","journal-title":"AJP Rep"},{"key":"bibr17-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.11.008"},{"key":"bibr18-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.9.945"},{"key":"bibr19-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813487681"},{"key":"bibr20-0003489419832629","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.11.1303"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0003489419832629","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0003489419832629","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0003489419832629","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:32:31Z","timestamp":1777375951000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0003489419832629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,19]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1177\/0003489419832629"],"URL":"https:\/\/doi.org\/10.1177\/0003489419832629","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,19]]}}}