{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:42:27Z","timestamp":1777426947253,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Office-based steroid injection has shown promise for idiopathic subglottic stenosis (iSGS). It is important to understand safety and patient-lived experience. We report patient experience related to airway restriction, voice, and side effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Sixteen patients (51\u2009\u00b1\u200914 years) with mild-moderate (20-50%) stenosis undergoing office-based transnasal steroid injections were included; fourteen had prior operations. Patients typically underwent three injections, 1\u2009month apart, followed by transnasal tracheoscopy 1\u2009month later to evaluate outcome; number of injections can vary based on disease severity and response. Outcomes were Dyspnea Index (DI), Modified Medical Research Council (MMRC) dyspnea scale, voice handicap index-10 (VHI-10), and degree of stenosis (estimated from procedural video). At each visit, patients were queried about post-injection airway restriction and side effects. Paired t-tests compared values at baseline versus follow-up tracheoscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>DI decreased ( t\u2009=\u20093.938, P\u2009=\u20090.0013), as did MMRC ( t\u2009=\u20092.179, P\u2009=\u20090.0457). There was no change in VHI-10 ( t\u2009=\u20091.354; P\u2009=\u20090.1957) scores. Airway stenosis decreased ( t\u2009=\u20094.331; P\u2009=\u20090.0006); this was not correlated with change in DI ( r\u2009=\u20090.267, P\u2009=\u20090.318). Side effects included airway restriction lasting &lt;48\u2009hours (n\u2009=\u20095), cough (n\u2009=\u20093), and nasal pain (n\u2009=\u20092).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Steroid injections improved upper airway symptoms. Side effects were mild and transient. Improvement in DI did not correlate with percent stenosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489419889066","type":"journal-article","created":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T01:06:28Z","timestamp":1574298388000},"page":"361-368","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":42,"title":["Office-Based Steroid Injections for Idiopathic Subglottic Stenosis: Patient-Reported Outcomes, Effect on Stenosis, and Side Effects"],"prefix":"10.1177","volume":"129","author":[{"given":"Matthew R.","family":"Hoffman","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2014Head and Neck Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David O.","family":"Francis","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2014Head and Neck Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnny P.","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2014Head and Neck Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3299-3014","authenticated-orcid":false,"given":"Seth H.","family":"Dailey","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2014Head and Neck Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"bibr1-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414548915"},{"key":"bibr2-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24956"},{"key":"bibr3-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25708"},{"key":"bibr4-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.4126"},{"key":"bibr5-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26682"},{"key":"bibr6-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26874"},{"key":"bibr7-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2017.2800"},{"key":"bibr8-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(90)90018-9"},{"key":"bibr9-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2013.12.017"},{"key":"bibr10-0003489419889066","first-page":"577","volume":"45","author":"Fletcher CM","year":"1952","journal-title":"Proc R Soc Med"},{"key":"bibr11-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2008.01832.x"},{"key":"bibr12-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200409000-00009"},{"key":"bibr13-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-0054-x"},{"key":"bibr14-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2006.00650.x"},{"key":"bibr15-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-007-9295-0"},{"key":"bibr16-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414564249"},{"key":"bibr17-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1177\/0003489415595425"},{"key":"bibr18-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-7258(02)00297-8"},{"key":"bibr19-0003489419889066","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909233411307"}],"container-title":["Annals of Otology, Rhinology &amp; 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