{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:00:45Z","timestamp":1789059645251,"version":"build-2803163510"},"reference-count":22,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100017551","name":"Children\u2019s National Medical Center","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100017551","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To explore long-term patient reported outcome (PRO) measures of pediatric paradoxical vocal cord motion (PVCM) including ease of diagnosis, management, symptom duration and effect on quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>All children &gt;8\u2009years of age diagnosed with PVCM at a tertiary pediatric hospital between 2006 and 2017 were invited to complete a survey addressing study objectives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>21\/47 eligible participants could be contacted and 18\/21 (86%) participated. 78% were female with a mean age at diagnosis of 11.6 and 15.0 years at survey completion. Common PVCM symptoms reported were dyspnea (89%), globus sensation (56%), and stridor (50%). The median time to diagnosis was 3\u2009months (IQR 2-5\u2009months). Nearly all reported being misdiagnosed with another condition, usually asthma, until being correctly diagnosed usually by an otolaryngologist. Participants reported undergoing 3.7 diagnostic studies (range 0-8); pulmonary function testing was most common. Of numerous treatments acknowledged, breathing exercises were common (89%) but only reported helpful by 56%. Use of biofeedback was recalled in 1\/3 of subjects but reported helpful in only 14% of them. Anti-reflux, allergy, anticholinergics, inhalers and steroids were each used in &gt;50%, but rarely reported effective. PVCM was reportedly a significant stressor when initially diagnosed but despite 2\/3 of participants still reporting ongoing PVCM symptoms, the perceived stress significantly decreased over time (Z\u2009=\u20093.26, P\u2009=\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This first PVCM PRO study endorses that diagnosis is often delayed and prescribed treatments often viewed as ineffective. While biofeedback and breathing exercises may be critical for short-term control of PVCM episodes, lifestyle changes and stress reduction are likely necessary for long-term management. Increased awareness and improvements in management are needed for this condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489420931894","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T04:12:41Z","timestamp":1591935161000},"page":"1195-1209","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Outcomes of Paradoxical Vocal Cord Motion Diagnosed in Childhood"],"prefix":"10.1177","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2035-6701","authenticated-orcid":false,"given":"Betel","family":"Yibrehu","sequence":"first","affiliation":[{"name":"The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Georgakopoulos","sequence":"additional","affiliation":[{"name":"The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela A.","family":"Mudd","sequence":"additional","affiliation":[{"name":"The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"},{"name":"Children\u2019s National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5202-5053","authenticated-orcid":false,"given":"Md Sohel","family":"Rana","sequence":"additional","affiliation":[{"name":"Children\u2019s National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9010-8511","authenticated-orcid":false,"given":"Nancy M.","family":"Bauman","sequence":"additional","affiliation":[{"name":"The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"},{"name":"Children\u2019s National Hospital, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"issue":"2016","key":"bibr1-0003489420931894","first-page":"165","volume":"90","author":"Hseu A","year":"2017","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"bibr2-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200110000-00016"},{"key":"bibr3-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.1.29"},{"key":"bibr4-0003489420931894","doi-asserted-by":"publisher","DOI":"10.3928\/00904481-20160331-01"},{"key":"bibr5-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815600144"},{"key":"bibr6-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2944"},{"key":"bibr7-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20985"},{"key":"bibr8-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1044\/0161-1461(2004\/034)"},{"key":"bibr9-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198306303082605"},{"key":"bibr10-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2017.01.027"},{"issue":"9","key":"bibr11-0003489420931894","volume":"1","author":"Dunn NM","year":"2015","journal-title":"Asthma Res Pract"},{"issue":"2012","key":"bibr12-0003489420931894","first-page":"31","volume":"76","author":"Rameau A","year":"2017","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"bibr13-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.1405"},{"key":"bibr14-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1044\/2015_AJSLP-14-0120"},{"issue":"5","key":"bibr15-0003489420931894","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1542\/peds.98.5.971","volume":"98","author":"Landweher L","year":"1996","journal-title":"Pediatrics"},{"key":"bibr16-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2013.07.025"},{"key":"bibr17-0003489420931894","volume":"11","author":"Fiorillo C","year":"2019","journal-title":"American Academy of Pediatrics News Bulletin"},{"key":"bibr18-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.4.7551399"},{"key":"bibr19-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199711000-00002"},{"key":"bibr20-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2014.07.018"},{"key":"bibr21-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2013.12.017"},{"key":"bibr22-0003489420931894","doi-asserted-by":"publisher","DOI":"10.1044\/2018_AJSLP-17-0223"}],"container-title":["Annals of Otology, Rhinology &amp; 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