{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T09:37:00Z","timestamp":1779269820747,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["TL1TR001415"],"award-info":[{"award-number":["TL1TR001415"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TL1TR001415"],"award-info":[{"award-number":["TL1TR001415"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To develop a smartphone application providing sound therapy and cognitive behavioral therapy (CBT) for treating tinnitus and performing a proof-of-concept pilot study evaluating its potential efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>An interactive smartphone application available on iOS and Android platforms was developed, which provided an 8-week tinnitus-specific CBT and personalized and frequency-matched sound therapy. Included patients presented to our tertiary clinic between 2017 and 2018, while those waitlisted were regarded as controls. Three surveys were administrated: Tinnitus Handicap Inventory (THI), Generalized Anxiety Disorder 7-item (GAD-7), and Perceived Stress Scale (PSS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 30 patients enrolled in this study consisting of 20 treatment and 10 control patients and mean age was 55.4\u2009\u00b1\u200911.6\u2009years. Treatment and control patients had similar age, sex, and pre-enrolment GAD and PSS (all P\u2009&gt;\u2009.05). Baseline THI scores were also similar between treatment and control cohorts (50.1\u2009\u00b1\u200921.9 vs 62.0\u2009\u00b1\u200920.7; P\u2009=\u2009.15). After 8\u2009weeks, though changes in GAD and PSS scores were similar ( P\u2009&gt;\u2009.05), the treatment group reported a significantly greater improvement in THI scores (17.7\u2009\u00b1\u200915.8 vs 5.3\u2009\u00b1\u200910.5, P\u2009=\u2009.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This pilot study demonstrated potentially promising efficacy of a smartphone-based CBT and sound therapy platform for treating tinnitus and encourages future randomized controlled trials on this treatment modality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003489420962818","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T05:24:45Z","timestamp":1602134685000},"page":"571-577","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Adapting Personal Therapies Using a Mobile Application for Tinnitus Rehabilitation: A Preliminary Study"],"prefix":"10.1177","volume":"130","author":[{"given":"Mehdi","family":"Abouzari","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0045-2547","authenticated-orcid":false,"given":"Khodayar","family":"Goshtasbi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke","family":"Sarna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser","family":"Ghavami","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica M.","family":"Parker","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3631-4760","authenticated-orcid":false,"given":"Pooya","family":"Khosravi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"},{"name":"Department of Biomedical Engineering, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Mostaghni","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrnaz","family":"Jamshidi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Saber","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2270-5207","authenticated-orcid":false,"given":"Hamid R.","family":"Djalilian","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"},{"name":"Department of Biomedical Engineering, University of California, Irvine, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,8]]},"reference":[{"key":"bibr1-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.1700"},{"key":"bibr2-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26107"},{"key":"bibr3-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(91)90033-K"},{"key":"bibr4-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010818-021556"},{"key":"bibr5-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1080\/14728214.2018.1555240"},{"key":"bibr6-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2010.12.006"},{"issue":"11","key":"bibr7-0003489420962818","volume":"11","author":"Hobson J","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr8-0003489420962818","doi-asserted-by":"publisher","DOI":"10.1007\/s10608-012-9476-1"},{"key":"bibr9-0003489420962818","first-page":"115","volume":"1","author":"Shulman A.","year":"1995","journal-title":"Int Tinnitus. 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