{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:21:41Z","timestamp":1777425701745,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To describe a rare presentation of laryngotracheal granulomatous disease secondary to sporotrichosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The authors report a case of laryngeal sporotrichosis in an immunocompromised patient, with accompanying endoscopic images and pathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results\/case:<\/jats:title>\n                    <jats:p>A 72-year-old immunocompromised female with a history of rose-handling presented with a year of hoarseness and breathy voice. Flexible nasolaryngoscopy showed diffuse nodularity; biopsy of the lesions demonstrated granulomatous inflammatory changes, and fungal culture grew Sporothrix schenkii. Long-term itraconazole treatment was initiated, with improvement in dysphonia and few residual granulomas on follow-up examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>When evaluating granulomatous disease of the airway, a broad differential including infectious or inflammatory etiologies should be considered, especially in immunocompromised patients. Adequate tissue samples should be collected to facilitate special staining. The current recommendations for laryngeal sporotrichosis include treatment with a prolonged course of itraconazole.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894211073002","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T02:16:59Z","timestamp":1641953819000},"page":"1404-1408","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Chronic Laryngotracheal Granulomatous Disease Secondary to\n                    <i>Sporothrix schenckii<\/i>\n                    in an Immunocompromised Patient"],"prefix":"10.1177","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2652-9418","authenticated-orcid":false,"given":"Hannah","family":"Kenny","sequence":"first","affiliation":[{"name":"University of Virginia School of Medicine, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3682-336X","authenticated-orcid":false,"given":"Michael","family":"Dougherty","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Churnin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of Virginia, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Early","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of Virginia, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akriti","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Virginia, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5735-1843","authenticated-orcid":false,"suffix":"Jr.","given":"Patrick O.","family":"McGarey","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of Virginia, Charlottesville, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"key":"bibr1-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/272376"},{"key":"bibr2-00034894211073002","doi-asserted-by":"publisher","DOI":"10.3390\/jof4020062"},{"key":"bibr3-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(03)00089-2"},{"key":"bibr4-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198505000-00014"},{"key":"bibr5-00034894211073002","doi-asserted-by":"publisher","DOI":"10.5858\/2003-127-893-LARTSA"},{"key":"bibr6-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.05.002"},{"key":"bibr7-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.05.003"},{"key":"bibr8-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2015.05.001"},{"issue":"5","key":"bibr9-00034894211073002","first-page":"5093","volume":"14","author":"Zhao N","year":"2017","journal-title":"Exp Ther Med"},{"key":"bibr10-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2018.01.004"},{"key":"bibr11-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2018.12.006"},{"key":"bibr12-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2007.04.011"},{"key":"bibr13-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-213325"},{"key":"bibr14-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-017-0831-0"},{"key":"bibr15-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27492"},{"key":"bibr16-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2018.08.013"},{"key":"bibr17-00034894211073002","doi-asserted-by":"publisher","DOI":"10.3390\/jof5010008"},{"key":"bibr18-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70205-7"},{"key":"bibr19-00034894211073002","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2017.06.012"}],"container-title":["Annals of Otology, Rhinology &amp; 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