{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:03:08Z","timestamp":1777539788353,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T00:00:00Z","timestamp":1644192000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Carotid sinus syndrome (CSS) is a rare yet serious presentation of head and neck malignancy. To our knowledge, syncope and seizure-like episodes as a manifestation of carotid sinus syndrome secondary to laryngeal cancer has not been reported to date. We report a case of laryngeal cancer causing convulsive syncope masquerading as seizures due to CSS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Case report. The patient\u2019s medical record was reviewed for demographic and clinical information.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A 62-year-old male presented with multiple episodes of syncope and hoarseness of voice. On nasoendoscopic examination, left vocal cord palsy and left aryepiglottic fold tumor were visualized. Computerized tomography (CT) neck showed a large 2.4\u2009\u00d7\u20093.6\u2009cm left supraglottic tumor with local invasion and extensive cervical lymphadenopathy compressing the carotid sinus. CT guided biopsy of the tumor revealed invasive squamous cell carcinoma. While undergoing evaluation, the patient developed seizure-like episodes. Inpatient telemetry monitoring revealed significant bradycardia and hypotension during these episodes. A permanent pacemaker was inserted which resulted in resolution of the syncopal and seizure-like episodes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In patients with unexplained syncope or seizure-like episodes and a background of head and neck cancer, clinicians should consider the diagnosis of CSS. CSS is a poor prognostic factor due to the associated higher stage of disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894221076573","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T23:50:26Z","timestamp":1644277826000},"page":"100-104","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Convulsive Syncope From Carotid Sinus Syndrome as a Manifestation of Laryngeal Cancer"],"prefix":"10.1177","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3111-3054","authenticated-orcid":false,"given":"Joel","family":"Goh Co Ian","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Changi General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2474-7147","authenticated-orcid":false,"given":"Xinyong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Changi General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Judith","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Changi General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tee Sin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Changi General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,7]]},"reference":[{"key":"bibr1-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.03.003"},{"key":"bibr2-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy037"},{"key":"bibr3-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1979.03630480061019"},{"key":"bibr4-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380050221031"},{"issue":"2","key":"bibr5-00034894221076573","first-page":"127","volume":"44","author":"Thomas JE.","year":"1969","journal-title":"Mayo Clin Proc"},{"key":"bibr6-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1007\/BF00165610"},{"key":"bibr7-00034894221076573","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-9-10-1380"},{"key":"bibr8-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198904000-00004"},{"key":"bibr9-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(58)90211-X"},{"key":"bibr10-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.76.900.656"},{"key":"bibr11-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1684\/epd.2009.0281"},{"key":"bibr12-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-193309000-00003"},{"key":"bibr13-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90261-M"},{"key":"bibr14-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1983.93.10.1290"},{"key":"bibr15-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(81)90287-4"},{"key":"bibr16-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(85)90255-8"},{"key":"bibr17-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1186\/1746-160X-8-31"},{"key":"bibr18-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(34)90473-7"},{"key":"bibr19-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100084486"},{"key":"bibr20-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.47.5.411"},{"key":"bibr21-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1053\/clon.2000.9201"},{"key":"bibr22-00034894221076573","doi-asserted-by":"publisher","DOI":"10.1177\/153857447500900404"},{"issue":"2","key":"bibr23-00034894221076573","volume":"12","author":"Toscano M","year":"2020","journal-title":"Cureus"}],"container-title":["Annals of Otology, Rhinology &amp; 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