{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:45:58Z","timestamp":1785800758116,"version":"3.56.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T00:00:00Z","timestamp":1654214400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Hypopharyngeal and laryngeal cancers are aggressive and usually diagnosed at advanced stage with esophagus invasion. Total pharyngolaryngoesophagectomy with gastric pull-up reconstruction has been a common surgery for these cancers but long-term outcomes are still questionable. This study aimed to investigate short-term and long-term outcomes of patients who underwent this surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with hypopharyngeal or laryngeal cancer invading cervical esophagus who underwent total pharyngolaryngoesphagectomy with gastric pull-up between 2012 and 2016 was included and followed up until 2021. Short-term outcomes were complications and long-term outcomes were overall survival (OS) and disease-free survival (DFS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifty patients were included with a mean age of 60.3\u2009years and 94% were male. Pyriform fossa was the most common primary site of tumor (50%), followed by posterior hypopharyngeal wall (18%) and postcricoid region (18%). Mean operating time, postoperative oral intake and hospital stay was 363.1\u2009\u00b1\u200943.6\u2009minutes, 8.8\u2009\u00b1\u20093.6\u2009days and 14.2\u2009\u00b1\u20093.0\u2009days respectively. Complications occurred in 15 patients (30%) without any in-hospital death. During the follow-up period, 17 patients had recurrence and 35 patients died. Median (95% confidence interval [CI]) OS and DFS time were 30 (21-37) and 30 (19-36) months. Five-year OS and DFS probability (95% CI) were 22.6% (12.8-39.7) and 22.7% (12.9-39.8).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Total pharyngolaryngoesophagectomy with gastric pull-up is feasible and safe. However, even with curative surgery and multimodal treatment, advanced pharyngeal or laryngeal cancer with cervical esophagus invasion still has poor survival outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894221098802","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T04:54:04Z","timestamp":1654232044000},"page":"511-518","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Long-Term Survival of Patients After Total Pharyngolaryngoesophagectomy With Gastric Pull-Up Reconstruction for Hypopharyngeal or Laryngeal Cancer Invading Cervical Esophagus"],"prefix":"10.1177","volume":"132","author":[{"given":"Tran Anh","family":"Bich","sequence":"first","affiliation":[{"name":"Otorhinolaryngology Department, Cho Ray hospital, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2684-3041","authenticated-orcid":false,"given":"Nguyen Lam","family":"Vuong","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics and Informatics, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Cong Huyen Ton Nu","family":"Cam Tu","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department, ENT Hospital, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran Minh","family":"Truong","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Department, Cho Ray hospital, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-5165","authenticated-orcid":false,"given":"Lam Viet","family":"Trung","sequence":"additional","affiliation":[{"name":"Digestive Surgery Department, Cho Ray hospital, Ho Chi Minh City, Vietnam"},{"name":"Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,3]]},"reference":[{"key":"bibr1-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21022"},{"key":"bibr2-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318173dc4a"},{"key":"bibr3-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1016\/s0959-8049(98)00328-1"},{"key":"bibr4-00034894221098802","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.97462"},{"key":"bibr5-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1007\/s004230050008"},{"key":"bibr6-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890060510"},{"issue":"6","key":"bibr7-00034894221098802","first-page":"849","volume":"25","author":"Shefts LM","year":"1949","journal-title":"Surgery"},{"key":"bibr8-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199001000-00004"},{"key":"bibr9-00034894221098802","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90146-5"},{"key":"bibr10-00034894221098802","unstructured":"R Core Team. 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