{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:42:18Z","timestamp":1791830538805,"version":"4.3.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["TL1TR001415"],"award-info":[{"award-number":["TL1TR001415"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TL1TR001415"],"award-info":[{"award-number":["TL1TR001415"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the efficacy of a smartphone-based application providing tinnitus-specific cognitive behavioral therapy and customized sound therapy for tinnitus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In a prospective randomized controlled trial, the treatment group participated in daily sound therapy and weekly interactive CBT modules, and the control group did not receive the program (waitlisted). Outcome measures after 8\u2009weeks included the Tinnitus Functional Index (TFI), Generalized Anxiety Disorder (GAD-7), Patient Health Questionnaire (PHQ-9), Perceived Stress Scale (PSS), and Pittsburgh Sleep Quality Index (PSQI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Ninety-two patients (mean age\u2009=\u200957.2\u2009\u00b1\u200911.9\u2009years) were included. The treatment (n\u2009=\u200947) and control (n\u2009=\u200945) cohorts had similar TFI, PHQ-9, GAD-7, PSS, and PSQI scores at presentation (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&gt;\u2009.05). Treatment-group patients had significantly higher improvements than controlled patients in their TFI (16.7\u2009\u00b1\u200914.9 vs 1.9\u2009\u00b1\u200910.8,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001), PHQ-9 (1.9\u2009\u00b1\u20094.2 vs \u22120.7\u2009\u00b1\u20093.4,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.002), GAD-7 (1.1\u2009\u00b1\u20093.6 vs \u22120.9\u2009\u00b1\u20093.3,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.009), and PSQI scores (2.5\u2009\u00b1\u20093.2 vs \u22121.1\u2009\u00b1\u20092.1,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Treatment-group subjects also significantly improved in 7 of the 8 TFI domains (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05). TFI improvements of \u226520 occurred in 18 (38.3%) treatment subjects. Of the 9 treatment-group patients presenting with moderate-severe depression, 4 (44.4%) improved to minimal depression. Of the 4 treatment-group patients with moderate-severe anxiety, 2 (50.0%) improved to minimal anxiety. Of the 17 treatment-group patients with moderate-severe sleep difficulties, 10 (55.6%) had considerable sleep improvement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This novel smartphone application providing cognitive behavioral therapy and customized sound therapy was effective in reducing symptom severity and improving anxiety, sleep, and mood for tinnitus patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894241297594","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T01:03:30Z","timestamp":1730941410000},"page":"125-133","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Smartphone-Based Cognitive Behavioral Therapy and Customized Sound Therapy for Tinnitus: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"134","author":[{"given":"Khodayar","family":"Goshtasbi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Tawk","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooya","family":"Khosravi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"},{"name":"Department of Biomedical Engineering, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3585-698X","authenticated-orcid":false,"given":"Mehdi","family":"Abouzari","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid R.","family":"Djalilian","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, CA, USA"},{"name":"Department of Biomedical Engineering, University of California, Irvine, CA, USA"},{"name":"Department of Neurosurgery, University of California, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.1700"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-014-2973-7"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(02)00168-8"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2015.08.014"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/16513860410027349"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00802"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2010.12.006"},{"issue":"11","key":"e_1_3_2_9_2","article-title":"Sound therapy (masking) in the management of tinnitus in adults","volume":"2012","author":"Hobson J","unstructured":"Hobson J, Chisholm E, El Refaie A. 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