{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:41:47Z","timestamp":1780393307949,"version":"3.54.1"},"reference-count":30,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with a strong impact on the quality of life (QoL) which treatment is based on local intranasal corticosteroids (ICS) and iterative courses of systemic corticosteroids (SCS) in case of relapse. When medical treatment is insufficient, surgery is indicated. We investigated the impact of enlarged frontal sinusotomies (EFS: Draf IIb or Draf III) on QoL and annual SCS consumption of patients with severe uncontrolled CRSwNP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a retrospective cohort study of 38 patients, who underwent EFS at Lariboisi\u00e8re University Hospital (CHU) in Paris, France, between 2006 and 2020. All patients were asked to complete SNOT-22 questionnaires concerning pre- and post-op status. Patients\u2019 medical and sinus surgery history as well as the number of SCS treatments per year before and after surgery were also collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 38 patients, 33 underwent a Draf III procedure and 5 a Draf IIb, with no major complications reported. Surgery resulted in a significant improvement in SNOT-22 scores (\u221232.7\u2009\u00b1\u200919.3, P\u2009&lt;\u20090.001), with 19\/22 items improving significantly. The number of annual SCS treatments decreased significantly from a mean of 4.8\u2009\u00b1\u20094.3 to 0.6\u2009\u00b1\u20091.2 ( P\u2009&lt;\u20090.001). During the follow-up (mean 88\u2009months), 95% of our patients showed a satisfying disease control and only 2 patients required revision surgery for poor disease control 5\u2009years after EFS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>EFS appears to be an effective and durable therapeutic option to improve the QoL of patients with severe CRSwNP and to reduce their SCS consumption without major complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894241298749","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T23:47:16Z","timestamp":1731368836000},"page":"195-200","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Enlarged Frontal Sinusotomy and Chronic Rhinosinusitis with Nasal Polyps: An Effective Strategy to Control the Disease"],"prefix":"10.1177","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8349-9569","authenticated-orcid":false,"given":"Tommaso","family":"Saccardo","sequence":"first","affiliation":[{"name":"Department of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy"},{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentine","family":"Nicolas","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7540-7265","authenticated-orcid":false,"given":"Emilien","family":"Chebib","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, AP-HP, Robert Debre Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Manca di Villahermosa","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"},{"name":"Department of Surgery, Unit of Otorhinolaryngology, University of Cagliari, Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0611-4570","authenticated-orcid":false,"given":"Benjamin","family":"Verillaud","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Vinciguerra","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Herman","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology and Skull Base Center, AP-HP, Hospital Lariboisi\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"bibr1-00034894241298749","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.600"},{"key":"bibr2-00034894241298749","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin19.468"},{"key":"bibr3-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2020.1815682"},{"key":"bibr4-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.12.027"},{"key":"bibr5-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1136\/bmjoq-2017-000209"},{"key":"bibr6-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22264"},{"key":"bibr7-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21739"},{"key":"bibr8-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.11.013"},{"key":"bibr9-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1177\/000348941112000304"},{"key":"bibr10-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23610"},{"key":"bibr11-00034894241298749","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin19.184"},{"key":"bibr12-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24422"},{"key":"bibr13-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13044"},{"key":"bibr14-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22032"},{"key":"bibr15-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20565"},{"key":"bibr16-00034894241298749","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2016.00220"},{"key":"bibr17-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22093"},{"key":"bibr18-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.02.016"},{"key":"bibr19-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.523"},{"key":"bibr20-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00457-4"},{"key":"bibr21-00034894241298749","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12091526"},{"key":"bibr22-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22780"},{"key":"bibr23-00034894241298749","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13081241"},{"key":"bibr24-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1111\/all.15772"},{"key":"bibr25-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28648"},{"key":"bibr26-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31881-1"},{"key":"bibr27-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2022.2090342"},{"key":"bibr28-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1177\/014556131809700918"},{"key":"bibr29-00034894241298749","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin21.017"},{"key":"bibr30-00034894241298749","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22865"}],"container-title":["Annals 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