{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T21:23:55Z","timestamp":1786397035563,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>We sought to objectively characterize functional quality of life and social anxiety metrics in patients with retrograde \u2013 cricopharyngeus dysfunction (R-CPD) using validated questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A survey was posted to a private R-CPD Facebook group and a public R-CPD Reddit group. The survey contained demographic and clinical questions, as well as the PROMIS-29 questionnaire and the Social Anxiety Questionnaire (SAQ). The PROMIS-29 questionnaire contains 7 subdomains of quality of life functioning and is scored against a national average. The SAQ is a 30-item questionnaire with 5 subdomains of social anxiety. Comparisons of means were performed using\n                      <jats:italic>t<\/jats:italic>\n                      -tests and logistic regressions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Survey results from 239 respondents were included. The majority of respondents were young (&lt;30\u2009years, 51.1%) and female (73.6%). Two hundred twenty (92.1%) reported all 3 cardinal R-CPD symptoms and were included in the analysis of PROMIS-29 and SAQ results. On the PROMIS-29 questionnaire, respondents reported high levels of anxiety (71.0%), depression (55.1%), fatigue (66.8%), sleep impairment (43.0%), social avoidance (54.3%), and pain impairment (58.8%). The mean SAQ score was 96.4, with 52.0% of respondents scoring above the cutoff for social anxiety. Reported anxiety was highest in interactions with strangers (71.1%, 95% confidence interval [CI]: 64.3%-77.9%) and lowest in interactions with the sex 1 is attracted to (44.5%, 95% CI: 37.0%-52.0%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with R-CPD have high levels of anxiety and other impairment. Results may help clinicians understand and treat patients with R-CPD, and provide benchmarks by which clinicians may better monitor response to therapy, and provide benchmarks for clinicians to better monitor therapy response.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894251342088","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T02:34:17Z","timestamp":1748313257000},"page":"663-670","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Health-Related Quality of Life Metrics in Patients With Retrograde Cricopharyngeus Dysfunction"],"prefix":"10.1177","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5280-1254","authenticated-orcid":false,"given":"Daniel","family":"Jacobs","sequence":"first","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5701-1488","authenticated-orcid":false,"given":"Julia E.","family":"Duffy","sequence":"additional","affiliation":[{"name":"Tufts University School of Medicine, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8715-4533","authenticated-orcid":false,"given":"Michael Z.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(97)00323-9"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X19834553"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30346"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.1005655"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X20938342"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14721"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13020413"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31157"},{"key":"e_1_3_3_10_2","unstructured":"PROMIS\u00ae Score Cut Points. HealthMeasures. Accessed June 16 2024. https:\/\/www.healthmeasures.net\/score-and-interpret\/interpret-scores\/promis\/promis-score-cut-points"},{"issue":"1","key":"e_1_3_3_11_2","first-page":"5","article-title":"Validation of the Social Anxiety Questionnaire for Adults (SAQ-A30) with Spanish university students: similarities and differences among degree subjects and regions","volume":"18","author":"Caballo VE","year":"2010","unstructured":"Caballo VE, Salazar IC, Arias B, Irurtia MJ, Calderero M, CISO-A Research Team Spain. Validation of the Social Anxiety Questionnaire for Adults (SAQ-A30) with Spanish university students: similarities and differences among degree subjects and regions. Behavioral Psychology. 2010;18(1):5-34.","journal-title":"Behavioral Psychology"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0038828"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu13124494"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2021.05.031"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.104B4.BJJ-2021-1089.R1"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/21501327211030413"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpain.2021.682072"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/rssa.12058"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11524-019-00418-5"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-021-00234-w"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.7071"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.2196\/31231"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00034894251342088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00034894251342088","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00034894251342088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:31:15Z","timestamp":1777375875000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00034894251342088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,26]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1177\/00034894251342088"],"URL":"https:\/\/doi.org\/10.1177\/00034894251342088","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,26]]}}}