{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:52:57Z","timestamp":1792734777527,"version":"4.5.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      Neonatal suppurative sialadenitis (NSS) is an uncommon but serious complication of salivary gland infection, with few cases reported in literature, most often affecting preterm infants. Typical cases involve the parotid gland and are caused by\n                      <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                      infection. Contributing factors include prematurity, dehydration, prolonged hospitalisation, and immature immunity. Sequential bilateral gland involvement through haematogenous spread is rare, and presents significant management challenges in prematurity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation:<\/jats:title>\n                    <jats:p>\n                      We report the case of a preterm infant, born at 30\u2009weeks gestation, who spontaneously developed acute left-sided parotid swelling at 3\u2009weeks old in NICU. Inflammatory markers were significantly elevated and blood cultures grew\n                      <jats:italic toggle=\"yes\">Staphylococcus epidermidis<\/jats:italic>\n                      . Initial treatment was with broad-spectrum intravenous antibiotics, and after no significant improvement, confirmatory ultrasound, and subsequent bedside percutaneous drainage was performed by ear, nose, and throat (ENT) surgeons. Subsequently, they developed a second abscess in the contralateral submandibular gland, needing further bedside aspiration. Pus cultures isolated\n                      <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                      , and they improved with culture-driven antibiotics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>We highlight the importance of combining early antimicrobial therapy with minimally invasive procedural intervention in managing NSS, as well as the rarity of multiple, sequential gland involvement. Early drainage limits progression when empirical treatment fails and helps guide antimicrobial choice. It minimises the need for more invasive surgical intervention, which is complex in preterm infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A high index of suspicion, early minimally invasive drainage and prompt initiation of targeted antibiotics, are key to optimal outcomes in NSS, particularly in preterm infants at higher risk of severe disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00034894251410819","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:26:22Z","timestamp":1769167582000},"page":"472-475","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal Suppurative Sialadenitis With Bilateral Gland Involvement in a Preterm Infant: A Rare Complication of Bacteraemia"],"prefix":"10.1177","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8846-9301","authenticated-orcid":false,"given":"Anushka","family":"Ghosal","sequence":"first","affiliation":[{"name":"ENT, Lister Hospital, East &amp; North Hertfordshire NHS Trust, Stevenage, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-034X","authenticated-orcid":false,"given":"Johan","family":"Bastianpillai","sequence":"additional","affiliation":[{"name":"ENT, Lister Hospital, East &amp; North Hertfordshire NHS Trust, Stevenage, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis A.","family":"Dimitriadis","sequence":"additional","affiliation":[{"name":"ENT, Lister Hospital, East &amp; North Hertfordshire NHS Trust, Stevenage, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"issue":"3","key":"e_1_3_3_2_2","first-page":"321","article-title":"Neonatal suppurative parotitis: report of three cases and review of the literature","volume":"68","author":"Ismail EA","year":"2004","unstructured":"Ismail EA, Al-Haddad AM, Ghazaly MM, et al. Neonatal suppurative parotitis: report of three cases and review of the literature. Int J Pediatr Otorhinolaryngol. 2004;68(3):321-326.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"4","key":"e_1_3_3_3_2","first-page":"409","article-title":"Neonatal suppurative parotitis: a 7-year review","volume":"31","author":"Yarden-Bilavsky H","year":"2012","unstructured":"Yarden-Bilavsky H, Ben-Shimol S, Kassis I, et al. Neonatal suppurative parotitis: a 7-year review. Pediatr Infect Dis J. 2012;31(4):409-411.","journal-title":"Pediatr Infect Dis J"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000105181.74169.16"},{"issue":"1","key":"e_1_3_3_5_2","first-page":"72","article-title":"Bilateral neonatal suppurative parotitis: a rare occurrence","volume":"116","author":"Nguyen CV","year":"2002","unstructured":"Nguyen CV, Tong MC, Chan DK, et al. Bilateral neonatal suppurative parotitis: a rare occurrence. J Laryngol Otol. 2002;116(1):72-73.","journal-title":"J Laryngol Otol"},{"issue":"1","key":"e_1_3_3_6_2","first-page":"79","article-title":"Neonatal suppurative parotitis: a case report and review","volume":"67","author":"Bitar MA","year":"2003","unstructured":"Bitar MA, Soudki MA. Neonatal suppurative parotitis: a case report and review. Int J Pediatr Otorhinolaryngol. 2003;67(1):79-82.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306213"},{"issue":"6","key":"e_1_3_3_8_2","first-page":"1175","article-title":"Risk factors for Staphylococcus epidermidis bloodstream infection in neonatal intensive care unit patients","volume":"105","author":"Saiman L","year":"2000","unstructured":"Saiman L, Ludington E, Dawson JD, et al. Risk factors for Staphylococcus epidermidis bloodstream infection in neonatal intensive care unit patients. Pediatrics. 2000;105(6):1175-1180.","journal-title":"Pediatrics"},{"issue":"4","key":"e_1_3_3_9_2","first-page":"577","article-title":"Ultrasonography of the salivary glands in infants and children","volume":"4","author":"Razek AAKA","year":"2009","unstructured":"Razek AAKA, El-Hamesy M, Megahed AS, et al. Ultrasonography of the salivary glands in infants and children. Ultrasound Clin. 2009;4(4):577-588.","journal-title":"Ultrasound Clin"},{"issue":"2","key":"e_1_3_3_10_2","first-page":"123","article-title":"Conservative management of deep neck infections in children","volume":"45","author":"Talmi YP","year":"1998","unstructured":"Talmi YP, Goldschmied-Reouven A, Finkelstein Y, et al. Conservative management of deep neck infections in children. Int J Pediatr Otorhinolaryngol. 1998;45(2):123-130.","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"7","key":"e_1_3_3_11_2","first-page":"242","article-title":"Peritonsillar and retropharyngeal abscesses","volume":"25","author":"Wald ER.","year":"2004","unstructured":"Wald ER. Peritonsillar and retropharyngeal abscesses. Pediatr Rev. 2004;25(7):242-246.","journal-title":"Pediatr Rev"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00034894251410819","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00034894251410819","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00034894251410819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:47:50Z","timestamp":1777549670000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00034894251410819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,23]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1177\/00034894251410819"],"URL":"https:\/\/doi.org\/10.1177\/00034894251410819","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,23]]}}}