{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:09:20Z","timestamp":1777424960379,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1975,5,1]],"date-time":"1975-05-01T00:00:00Z","timestamp":168134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1975,5]]},"abstract":"<jats:p>An experiment was performed on 31 guinea pigs to study the effect of fistulae of the horizontal canal, superior canal, common crus, and utricle on the course of experimentally induced endolymphatic hydrops. The effect of fistulae on corresponding parts of normal ears was also studied in an additional 17 animals. The results indicated a remarkable consistency in healing of the fistulae in both groups of animals. Fistulae had no significant effect on the course of endolymphatic hydrops, irrespective of whether the fistulae were made immediately before or several months after obliteration of the endolymphatic duct or whether a polyethylene strut was introduced into the membranous labyrinth. Once again, the functional significance of the endolymphatic sac was clearly apparent, for ablation of the sac consistently produced severe hydrops and atrophic changes in sensory and neural structures. Assuming that the mechanisms of labyrinth repair in the guinea pig are comparable to the higher mammalian ear, it is apparent that procedures designed to surgically fistulize the membranous labyrinth are of questionable value and are probably not rational therapeutic approaches to the management of M\u00e9ni\u00e8re's disease.<\/jats:p>","DOI":"10.1177\/000348947508400301","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:29:51Z","timestamp":1412346591000},"page":"271-286","source":"Crossref","is-referenced-by-count":31,"title":["Effect of Fistulae on Endolymphatic Hydrops"],"prefix":"10.1177","volume":"84","author":[{"given":"Robert S.","family":"Kimura","sequence":"first","affiliation":[{"name":"Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold F.","family":"Schuknecht","sequence":"additional","affiliation":[{"name":"Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1975,5,1]]},"reference":[{"key":"bibr1-000348947508400301","first-page":"145","volume":"78","author":"Cawthorne T","year":"1949","journal-title":"Acta Otolaryngol"},{"key":"bibr2-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33321-1"},{"key":"bibr3-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33322-3"},{"key":"bibr4-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33323-5"},{"key":"bibr5-000348947508400301","first-page":"343","volume":"27","author":"Kimura RS","year":"1965","journal-title":"Pract Otorhinolaryngol"},{"key":"bibr6-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1177\/000348946707600311"},{"key":"bibr7-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33279-5"},{"key":"bibr8-000348947508400301","unstructured":"Femenic B: Personal communication."},{"key":"bibr9-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1177\/000348946907800311"},{"key":"bibr10-000348947508400301","unstructured":"Lim DJ, Silver P: Scanning electron microscopic morphology of the endolymphatic duct system. Presented at the B\u00e1r\u00e1ny Society Meeting, June, 1974, Anaheim, California."},{"key":"bibr11-000348947508400301","first-page":"305","volume-title":"Otosclerosis.","author":"Hohmann A","year":"1962"},{"key":"bibr12-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1177\/000348946207100417"},{"key":"bibr13-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1959.03010320017005"},{"key":"bibr14-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)33280-1"},{"key":"bibr15-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1177\/000348946707600312"},{"key":"bibr16-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196507000-00002"},{"key":"bibr17-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196604000-00009"},{"key":"bibr18-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1177\/000348945706600301"},{"key":"bibr19-000348947508400301","doi-asserted-by":"publisher","DOI":"10.3109\/00016486809120990"},{"key":"bibr20-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1121\/1.1978077"},{"key":"bibr21-000348947508400301","unstructured":"Silverstein H: Biochemistry of the inner ear following endolymphatic sac obliteration. Presented at the B\u00e1r\u00e1ny Society Meeting, June, 1974, Anaheim, California."},{"key":"bibr22-000348947508400301","first-page":"932","volume":"70","author":"Nakamura T","year":"1967","journal-title":"Jap J Otol Tokyo"},{"key":"bibr23-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196603000-00007"},{"key":"bibr24-000348947508400301","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1966.00760030397003"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348947508400301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348947508400301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:28:08Z","timestamp":1777375688000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348947508400301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1975,5]]}},"alternative-id":["10.1177\/000348947508400301"],"URL":"https:\/\/doi.org\/10.1177\/000348947508400301","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,5]]}}}