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Prognosis can be predicted according to the slope of the initial audiogram (low-frequency losses do better than high-frequency losses), hearing at 8 kHz, erythrocyte sedimentation rates, in some select instances spatial disorientation symptoms, and speech discrimination scores. There was a very poor correlation between hearing and vestibular test abnormalities, except hypoactive calorics. There were no correlations with age (excepting the very elderly), with antecedent respiratory infections. hypertension, diabetes, or other chronic diseases. We conclude that there is a fundamental difference in the behavior of apical and basal cochlea losses, that hearing recovery is always better at low than at high frequencies, that because of the high spontaneous recovery rates, tympanotomies seeking perilymph fistulas should be delayed ten days unless there is a progressive hearing loss, and that none of the current recommended treatments, especially histamine, have any effect on the outcome.<\/jats:p>","DOI":"10.1177\/000348947708600406","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:29:51Z","timestamp":1412346591000},"page":"463-480","source":"Crossref","is-referenced-by-count":565,"title":["Natural History of Sudden Sensorineural Hearing Loss"],"prefix":"10.1177","volume":"86","author":[{"given":"Douglas E.","family":"Mattox","sequence":"first","affiliation":[{"name":"Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. 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