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Of 58 ears studied in 29 patients, 19 demonstrated significant partial improvement in hearing during treatment. However, 11 ears returned to pretreatment hearing levels after therapy, and only 8 ears, or 15%, maintained the hearing gains one year later. Enhanced discrimination occurred more commonly than gains in pure tone threshold. Long-term alternate day prednisone therapy was required to sustain hearing improvement in a small number of patients.<\/jats:p>","DOI":"10.1177\/000348947908800202","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:29:51Z","timestamp":1412346591000},"page":"160-165","source":"Crossref","is-referenced-by-count":26,"title":["Treatment of Syphilitic Hearing Loss"],"prefix":"10.1177","volume":"88","author":[{"given":"Michael","family":"Zoller","sequence":"first","affiliation":[{"name":"Savannah, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William R.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Joseph B.","family":"Nadol","sequence":"additional","affiliation":[{"name":"Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1979,3,1]]},"reference":[{"key":"bibr1-000348947908800202","first-page":"252","volume":"30","author":"Tamari MJ","year":"1951","journal-title":"Eye Ear Nose Throat Mon"},{"key":"bibr2-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1978.00790020005001"},{"key":"bibr3-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-192805000-00001"},{"key":"bibr4-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1177\/000348943904800312"},{"key":"bibr5-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1966.00760020020008"},{"key":"bibr6-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-195211000-00003"},{"key":"bibr7-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1968.00760060380008"},{"key":"bibr8-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100076556"},{"key":"bibr9-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197306000-00003"},{"key":"bibr10-000348947908800202","first-page":"401","volume":"47","author":"Willcox RR","year":"1971","journal-title":"Br J Vener Dis"},{"key":"bibr11-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100043139"},{"key":"bibr12-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197511000-00012"},{"key":"bibr13-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1967.00980030049009"},{"key":"bibr14-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1969.00770030013005"},{"key":"bibr15-000348947908800202","first-page":"1","volume":"455","author":"WHO scientific group","year":"1970","journal-title":"WHO Tech Rep Ser"},{"key":"bibr16-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100052567"},{"key":"bibr17-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(62)90086-3"},{"key":"bibr18-000348947908800202","doi-asserted-by":"publisher","DOI":"10.1177\/000348944805700113"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348947908800202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348947908800202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:30:34Z","timestamp":1777375834000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348947908800202"}},"subtitle":["Combined Penicillin and Steroid Therapy in 29 Patients"],"short-title":[],"issued":{"date-parts":[[1979,3]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1979,3]]}},"alternative-id":["10.1177\/000348947908800202"],"URL":"https:\/\/doi.org\/10.1177\/000348947908800202","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,3]]}}}