{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:16:00Z","timestamp":1777425360025,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"6_suppl2","license":[{"start":{"date-parts":[[1980,11,1]],"date-time":"1980-11-01T00:00:00Z","timestamp":341884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1980,11]]},"abstract":"<jats:p>The clinical-histopathological correlation between Meni\u00e8re's disease and endolymphatic hydrops was done to explain, as much as possible, causes of symptoms of Meni\u00e8re's disease. Twenty-three temporal bones with endolymphatic hydrops from 17 patients were reviewed and clinical and histopathological findings were correlated. Histopathological examination revealed frequent, severe deformities in the labyrinthine walls and permanent changes in Reissner's membranes. Evidence of rupture was difficult to assess. Of 21 ears of patients with the clinical diagnosis of Meni\u00e8re's disease, 93% had endolymphatic hydrops. A statistical correlation between increased area of the cochlear duct and hearing loss was found. Some correlation was also found between frequency of vertigo and results of electronystagmography with histopathological findings. Consequently, the mechanical effect of endolymphatic hydrops seems to have greater significance in the production of symptoms of Meni\u00e8re's disease than the biochemical effect of ruptures. In a review of ten unusual cases from this series of 17 patients, traumatic neuromas or remnants of vestibular structures were found after an incomplete labyrinthectomy. Histopathological findings of four patients who had undergone endolymphatic subarachnoid shunt surgery are described.<\/jats:p>","DOI":"10.1177\/00034894800896s201","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T07:33:05Z","timestamp":1483687985000},"page":"2-22","source":"Crossref","is-referenced-by-count":87,"title":["Meni\u00e9re's Disease and Endolymphatic Hydrops Clinical-Histopathological Correlations"],"prefix":"10.1177","volume":"89","author":[{"given":"Bernard G.","family":"Fraysse","sequence":"first","affiliation":[{"name":"Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Alonso","sequence":"additional","affiliation":[{"name":"Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William F.","family":"House","sequence":"additional","affiliation":[{"name":"Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1980,11,1]]},"reference":[{"key":"bibr1-00034894800896S201","first-page":"597","volume":"16","author":"Meni\u00e8re P","year":"1861","journal-title":"Gaz Med Paris"},{"key":"bibr2-00034894800896S201","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100003947"},{"key":"bibr3-00034894800896S201","unstructured":"Friedmann I. Pathology of the ear. London: Blackwell Scientific Publications, 1974:479."},{"key":"bibr4-00034894800896S201","first-page":"133","volume":"39","author":"Wustrow F","year":"1960","journal-title":"Z Laryngol Rhinol Otol"},{"key":"bibr5-00034894800896S201","volume-title":"Endolymphatic hydrops and otitis media","author":"Paparella M","year":"1978"},{"key":"bibr6-00034894800896S201","first-page":"1927","volume":"171","author":"Lawrence M","year":"1959","journal-title":"(Meniere's syndrome.) 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