{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:01:35Z","timestamp":1787018495941,"version":"build-2736575974"},"reference-count":40,"publisher":"SAGE Publications","issue":"6_suppl2","license":[{"start":{"date-parts":[[1980,11,1]],"date-time":"1980-11-01T00:00:00Z","timestamp":341884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1980,11]]},"abstract":"<jats:p>The anatomy of the human endolymphatic duct system of three cases \u2014 one with Meni\u00e8re's syndrome (with no histopathological evidence of endolymphatic hydrops), one with Meni\u00e8re's disease (with histopathological evidence of endolymphatic hydrops), and one with no evidence of disease \u2014 has been studied by means of computer-aided and graphic reconstruction from serial sections of temporal bones. The reconstructions have revealed a canalicular arrangement of the epithelial lining of the rugose portion of the human endolymphatic sac. Accordingly, new nomenclature, \u201cpars canalicularis,\u201d is suggested for this portion. The computer produced lateral and medial views of the endolymphatic duct and sac of the patient with Meni\u00e8re's syndrome. The computer also calculated the luminal volume, the surface area of the epithelium, and the surface-to-volume ratio of the rugose portion of the sac.<\/jats:p>\n                  <jats:p>In addition, the authors graphically reconstructed the rugose portion of the sac of all three cases. Measurements of the dimensions of these reconstructions were made, from which the luminal volume was estimated. The reconstructed images and the calculations allowed quantitative comparison of the microscopic anatomy of the rugose portion of the sac in the Meni\u00e8re's syndrome and Meni\u00e8re's disease ears with that in an ear without evidence of disease.<\/jats:p>\n                  <jats:p>Significant differences were found in the volumes of the rugose portion of the sac of the three cases. The results suggest that the luminal volume of the rugose portion of the sac of Meni\u00e8re's disease patients may be significantly reduced. The authors speculate that endolymphatic hydrops may be the result of a loss of epithelial surface area in the canalicular portion, thus diminishing its resorptive function.<\/jats:p>\n                  <jats:p>The computer and graphic reconstruction techniques in conjunction with their analytical capabilities provide a new method for studying inner ear structures. These techniques have the potential to expand the capabilities of quantitative morphology and provide the means for deriving clinically useful data from histopathological and ultrastructural material.<\/jats:p>","DOI":"10.1177\/00034894800896s202","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T07:33:05Z","timestamp":1483687985000},"page":"23-32","source":"Crossref","is-referenced-by-count":22,"title":["Computer-Aided and Graphic Reconstruction of the Human Endolymphatic Duct and Sac"],"prefix":"10.1177","volume":"89","author":[{"given":"Juan-Carlos M.","family":"Antunez","sequence":"first","affiliation":[{"name":"Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred H.","family":"Linthicum","sequence":"additional","affiliation":[{"name":"Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank R.","family":"Galey","sequence":"additional","affiliation":[{"name":"Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert D.","family":"McCann","sequence":"additional","affiliation":[{"name":"Pasadena, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1980,11,1]]},"reference":[{"key":"bibr1-00034894800896S202","unstructured":"Cotugno D. De aquaeductibus auris humanae internae. 1760."},{"key":"bibr2-00034894800896S202","unstructured":"Boettcher A. Uber den Aqueductus Vestibuli bei Katzen und Menchen. 1869."},{"key":"bibr3-00034894800896S202","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000390102"},{"key":"bibr4-00034894800896S202","first-page":"446","volume":"39","author":"Sterzi G","year":"1909","journal-title":"Morphol Jahrb"},{"key":"bibr5-00034894800896S202","first-page":"1384","volume":"82","author":"Portmann G","year":"1919","journal-title":"C R Soc Biol"},{"key":"bibr6-00034894800896S202","unstructured":"Bast TH, Anson BJ. The temporal bone and the ear. Springfield: Charles C. 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