{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:20:45Z","timestamp":1777425645904,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1986,1,1]],"date-time":"1986-01-01T00:00:00Z","timestamp":504921600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1986,1]]},"abstract":"<jats:p>The temporal bones of a man with poorly differentiated lymphocytic lymphoma, who had had a bilateral conductive hearing loss and incomplete left-sided facial palsy, were obtained. Sections were prepared for histologic study by staining with hematoxylin and eosin and were examined under the light microscope. The left temporal bone showed marked tumor cell involvement, not only of the lateral part of the cartilaginous portion of the eustachian tube (ET) where the tensor veli palatini muscle had been partially destroyed, but also in the anterior part of the temporal bone. A serous middle ear effusion was present, but the lumen of the ET was unaffected by tumor or inflammation. The pathological findings in the right temporal bone were similar to those in the left, although the cartilaginous part of the ET and its surrounding structures were not available for study. The pathogenesis of otitis media with effusion appeared to be secondary to functional ET obstruction, due to the dysfunction of the tensor veli palatini muscle as a result of the tumor destruction. This case is the first to be reported in which functional ET obstruction, secondary to tumor invasion of the active muscle dilator of the ET, has been histologically confirmed.<\/jats:p>","DOI":"10.1177\/000348948609500121","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:35:41Z","timestamp":1412346941000},"page":"101-105","source":"Crossref","is-referenced-by-count":18,"title":["Lymphoma Invading the Anterior Eustachian Tube"],"prefix":"10.1177","volume":"95","author":[{"given":"Tetsuo","family":"Takahara","sequence":"first","affiliation":[{"name":"Kobe, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles D.","family":"Bluestone","sequence":"additional","affiliation":[{"name":"Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isamu","family":"Sando","sequence":"additional","affiliation":[{"name":"Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene N.","family":"Myers","sequence":"additional","affiliation":[{"name":"Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,1,1]]},"reference":[{"key":"bibr1-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1177\/000348946807700101"},{"key":"bibr2-000348948609500121","unstructured":"Z\u00f6llner R. Physiologie, pathologie und klinik der ohrtrompete XVI. Die tube und maligne tumoren der nachbarschaft. Berlin: Springer Verlag, 1942: 188\u2013207."},{"key":"bibr3-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1947.00690020189005"},{"key":"bibr4-000348948609500121","unstructured":"Graf K. Geschwulste des ohres und des kleinhirnbrukenwinkels. Stuttgart: George Thieme Verlag, 1952: 242\u20133."},{"key":"bibr5-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196912000-00009"},{"key":"bibr6-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1177\/000348947208100306"},{"key":"bibr7-000348948609500121","first-page":"293","volume":"18","author":"Rood SR","year":"1981","journal-title":"Cleft Palate J"},{"key":"bibr8-000348948609500121","first-page":"369","volume-title":"Pediatric otolaryngology","author":"Bluestone CD","year":"1983"},{"key":"bibr9-000348948609500121","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1288\/00005537-197704000-00004","volume":"87","author":"Bluestone CD","year":"1977","journal-title":"Laryngoscope"},{"key":"bibr10-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1973.00780020137016"},{"key":"bibr11-000348948609500121","first-page":"1325","volume":"76","author":"Bluestone CD","year":"1972","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"},{"key":"bibr12-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197501000-00009"},{"key":"bibr13-000348948609500121","first-page":"85","volume":"8","author":"Jahn AF","year":"1979","journal-title":"J Otolaryngol"},{"key":"bibr14-000348948609500121","first-page":"206","volume":"31","author":"Rich AR","year":"1920","journal-title":"Bull Johns Hopkins Hosp"},{"key":"bibr15-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1177\/000348947908800108"},{"key":"bibr16-000348948609500121","doi-asserted-by":"publisher","DOI":"10.3109\/00016487909126391"},{"key":"bibr17-000348948609500121","unstructured":"Moss WT, Brand WN, Battifora H. Radiation oncology. Rationale, technique, results. VI. The ear, nasopharynx, nasal fossa, and paranasal sinuses. St Louis: CV Mosby Co, 1973: 170\u201394."},{"key":"bibr18-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1974.00780030420003"},{"key":"bibr19-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197209000-00009"},{"key":"bibr20-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1177\/00034894760850S235"},{"key":"bibr21-000348948609500121","doi-asserted-by":"publisher","DOI":"10.1177\/00034894800890S313"},{"key":"bibr22-000348948609500121","first-page":"225","volume-title":"Disorders of the facial nerve","author":"Saito H","year":"1981"},{"key":"bibr23-000348948609500121","first-page":"132","volume-title":"Otolaryngology","author":"Boles R","year":"1980"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348948609500121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348948609500121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:29:46Z","timestamp":1777375786000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348948609500121"}},"subtitle":["Temporal Bone Histopathology of Functional Tubal Obstruction"],"short-title":[],"issued":{"date-parts":[[1986,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,1]]}},"alternative-id":["10.1177\/000348948609500121"],"URL":"https:\/\/doi.org\/10.1177\/000348948609500121","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,1]]}}}