{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:34:02Z","timestamp":1777426442285,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1988,1,1]],"date-time":"1988-01-01T00:00:00Z","timestamp":567993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:p>Many studies have been done recently to determine the role of various stresses on the heart and peripheral vasculature. Although damage to coronary arteries and renal vessels has been well described, the ear as an end-organ in small vessel disease has been largely neglected. In a previous study, we examined the effects of noise, hypertension, and an atherogenic diet on the microvasculature of the cochleas in rats. The present study examines the effects of these stresses on the hearts of the same rats. The technique used to examine microvascular blood flow was the injection of unlabeled microspheres prior to killing. We found that the blood flow in the cochleas was reduced significantly in hypertensive animals exposed to noise or an atherogenic diet compared to that of normotensive or hypertensive control animals. The hearts of such animals, however, showed decreased myocardial blood flow only when compared to those of normotensive control animals, not when compared to those of hypertensive control animals.<\/jats:p>","DOI":"10.1177\/000348948809700102","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:35:41Z","timestamp":1412346941000},"page":"9-13","source":"Crossref","is-referenced-by-count":20,"title":["Cochlea and Heart as End-Organs in Small Vessel Disease"],"prefix":"10.1177","volume":"97","author":[{"given":"James D.","family":"Sidman","sequence":"first","affiliation":[{"name":"Chapel Hill, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen H.","family":"Pulver","sequence":"additional","affiliation":[{"name":"Chapel Hill, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiri","family":"Prazma","sequence":"additional","affiliation":[{"name":"Chapel Hill, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Harold C.","family":"Pillsbury","sequence":"additional","affiliation":[{"name":"Chapel Hill, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1988,1,1]]},"reference":[{"key":"bibr1-000348948809700102","first-page":"573","volume":"54","author":"Kannel WB","year":"1978","journal-title":"Bull NY Acad Med"},{"key":"bibr2-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.2.254"},{"key":"bibr3-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330120023025"},{"key":"bibr4-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91908-6"},{"key":"bibr5-000348948809700102","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/01.CIR.41.1.1","volume":"41","author":"Keys A","year":"1970","journal-title":"Circulation"},{"key":"bibr6-000348948809700102","volume-title":"Estimating risk of coronary heart disease in daily practice","author":"Coronary risk handbook","year":"1973"},{"key":"bibr7-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197706232962507"},{"key":"bibr8-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1984.tb03611.x"},{"key":"bibr9-000348948809700102","unstructured":"Robbins S, Cotran R, Kumar S. Blood vessels. In: Pathologic basis of disease. 4th ed. Philadelphia: WB Saunders, 1984: 502\u201346"},{"key":"bibr10-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1978.tb06223.x"},{"key":"bibr11-000348948809700102","doi-asserted-by":"publisher","DOI":"10.3109\/00016488309132894"},{"key":"bibr12-000348948809700102","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409130987"},{"key":"bibr13-000348948809700102","doi-asserted-by":"publisher","DOI":"10.3109\/00016487709128818"},{"key":"bibr14-000348948809700102","volume-title":"The cochlear blood flow [Dissertation]","author":"Hultcrantz E.","year":"1978"},{"key":"bibr15-000348948809700102","unstructured":"Prazma J, Rodgers GK. The cochlear blood flow investigated by new microsphere-surface preparation method. Presented at the 19th Workshop on Inner Ear Biology, Mainz, Federal Republic of Germany, Sept 6, 1982"},{"key":"bibr16-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1986.03780020060014"},{"key":"bibr17-000348948809700102","unstructured":"Spector WS, ed. Handbook of biological data. Philadelphia: WB Saunders, 1956: 175."},{"key":"bibr18-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1016\/0160-5402(79)90028-7"},{"key":"bibr19-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198610000-00012"},{"key":"bibr20-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1177\/000348947808700321"},{"key":"bibr21-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1159\/000128092"},{"key":"bibr22-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1139\/y70-064"},{"key":"bibr23-000348948809700102","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/16.10.580"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348948809700102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348948809700102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:31:13Z","timestamp":1777375873000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348948809700102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1177\/000348948809700102"],"URL":"https:\/\/doi.org\/10.1177\/000348948809700102","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}