{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:58Z","timestamp":1777420858466,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1991,6,1]],"date-time":"1991-06-01T00:00:00Z","timestamp":675734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Otol Rhinol Laryngol"],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:p>In order to evaluate the prevalence of audiovestibular disturbances in Beh\u00e7et's syndrome, we submitted 20 consecutive patients and 20 control subjects to detailed audiologic and vestibular examination in the last 3 years. A sensorineural hearing loss was found in 12 patients, 2 of whom revealed sudden deafness. Two other patients with neuro-Beh\u00e7et's syndrome showed a vestibular function deficit, and 3 others exhibited altered caloric stimulation test results. Two of these last patients also revealed a simultaneous bilateral auditory deficit. HLA typing showed the presence of the B51 antigen in 10 of the 14 patients with ear involvement, while only 3 of the 6 patients without ear involvement were HLA-B51-positive. Results suggest that audiovestibular involvement is common in Beh\u00e7et's syndrome: Sudden deafness may be the first sign of ear disturbance; vestibular lesions may represent an early sign of neuro-Beh\u00e7et's syndrome; and the HLA-B51 antigen is associated with ear involvement. Otoneurologic study can reveal hidden brain stem lesions in Beh\u00e7et's patients during flare-ups of the disease, even without obvious signs of neurologic deficits.<\/jats:p>","DOI":"10.1177\/000348949110000606","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:38:05Z","timestamp":1412347085000},"page":"459-463","source":"Crossref","is-referenced-by-count":45,"title":["Hearing and Vestibular Disturbances in Beh\u00e7et's Syndrome"],"prefix":"10.1177","volume":"100","author":[{"given":"Gabriele","family":"Gemignani","sequence":"first","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Berrettini","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Bruschini","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Piragine","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Sellari-Franceschini","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampiero","family":"Pasero","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierfrancesco","family":"Fusari","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignazio","family":"Olivieri","sequence":"additional","affiliation":[{"name":"Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,6,1]]},"reference":[{"key":"bibr1-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.40.6.355"},{"key":"bibr2-000348949110000606","first-page":"1152","volume":"105","author":"Beh\u00e7et H","year":"1937","journal-title":"Dermatol Wochenschr"},{"key":"bibr3-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1159\/000253787"},{"key":"bibr4-000348949110000606","first-page":"991","volume-title":"Arthritis and allied conditions","author":"Ehrlich GE","year":"1989","edition":"11"},{"key":"bibr5-000348949110000606","first-page":"2579","volume":"69","author":"Alajouanine T","year":"1961","journal-title":"Presse Med"},{"key":"bibr6-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790280023004"},{"key":"bibr7-000348949110000606","first-page":"469","volume":"99","author":"Belkahia B","year":"1982","journal-title":"Ann Otolaryngol"},{"key":"bibr8-000348949110000606","first-page":"667","volume":"85","author":"Okamoto M","year":"1982","journal-title":"J Otolaryngol Jpn"},{"key":"bibr9-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1016\/S0248-8663(88)80043-2"},{"key":"bibr10-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1136\/ard.28.2.95"},{"key":"bibr11-000348949110000606","first-page":"116","volume":"61","author":"Bocca E","year":"1950","journal-title":"Arch Ital Otol Rinol Laringol"},{"key":"bibr12-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1952.00710010550003"},{"key":"bibr13-000348949110000606","first-page":"48","volume-title":"Nobel Symposium 10. Disorders of the skull base region","author":"Anderson H","year":"1969"},{"key":"bibr14-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1177\/000348947608500103"},{"key":"bibr15-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1159\/000276028"},{"key":"bibr16-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/65.2.115"},{"key":"bibr17-000348949110000606","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196712000-00003"},{"key":"bibr18-000348949110000606","first-page":"235","volume-title":"Recent advances in Beh\u00e7et's disease","volume":"103","author":"Inaba G","year":"1986"}],"container-title":["Annals of Otology, Rhinology &amp; Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348949110000606","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000348949110000606","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:15:23Z","timestamp":1777374923000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000348949110000606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1991,6]]}},"alternative-id":["10.1177\/000348949110000606"],"URL":"https:\/\/doi.org\/10.1177\/000348949110000606","relation":{},"ISSN":["0003-4894","1943-572X"],"issn-type":[{"value":"0003-4894","type":"print"},{"value":"1943-572X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,6]]}}}