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Striated ducts were mainly unaffected by irradiation. Arterioles showed slight to moderate narrowing of the lumina. There was an increased amount of plasma cells in the gland lobules at 10 months postirradiation. Histologic and morphometric criteria and changes in gland weight showed less pronounced radiation injury in glands irradiated during inhibition of the gland function by biperiden (Akineton) compared to glands irradiated during stimulation of the gland function by pilocarpine. This finding may offer a clinically important means to reduce salivary gland dysfunction after radiation treatment of tumors in the head and neck regions.<\/jats:p>","DOI":"10.1177\/000348949410300208","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:38:05Z","timestamp":1412347085000},"page":"125-134","source":"Crossref","is-referenced-by-count":16,"title":["Influence on Rabbit Submandibular Gland Injury by Stimulation or Inhibition of Gland Function during Irradiation"],"prefix":"10.1177","volume":"103","author":[{"given":"Bo H.","family":"Ahlner","sequence":"first","affiliation":[{"name":"Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evy","family":"Hagelqvist","sequence":"additional","affiliation":[{"name":"Uppsala, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magnus G.","family":"Lind","sequence":"additional","affiliation":[{"name":"Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,2,1]]},"reference":[{"key":"bibr1-000348949410300208","unstructured":"Rubin P, Casarett GW. 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