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The presence of the virus in these tissues causes a unique constellation of diagnostic histopathologic features, including florid follicular hyperplasia, follicle lysis, and productively HIV-1-infected multinucleated giant cells of probable dendritic cell origin. Serologic evaluation is confirmatory of HIV infection. With the recent advances in antiretroviral chemotherapy, the early institution of which may significantly prolong life and disease-free interval, the recognition of the clinical and pathologic parameters of HIV-related enlargement of Waldeyer's ring tissues is essential.<\/jats:p>","DOI":"10.1177\/000348949710600716","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:38:05Z","timestamp":1412347085000},"page":"611-618","source":"Crossref","is-referenced-by-count":12,"title":["Clinicopathological Consultation Human Immunodeficiency Virus-1 Infection of the Lymphoid Tissues of Waldeyer's Ring"],"prefix":"10.1177","volume":"106","author":[{"given":"Sarah S.","family":"Frankel","sequence":"first","affiliation":[{"name":"Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce M.","family":"Wenig","sequence":"additional","affiliation":[{"name":"Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfio","family":"Ferlito","sequence":"additional","affiliation":[{"name":"Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1997,7,1]]},"reference":[{"key":"bibr1-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1126\/science.3277274"},{"key":"bibr2-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.03.040185.002401"},{"key":"bibr3-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03340100047028"},{"key":"bibr4-000348949710600716","first-page":"977","volume":"109","author":"Ewing EP","year":"1985","journal-title":"Arch Pathol Lab Med"},{"key":"bibr5-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198309000-00005"},{"key":"bibr6-000348949710600716","first-page":"25","volume-title":"Progress in AIDS pathology","author":"Wood OS","year":"1990"},{"key":"bibr7-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870080050014"},{"key":"bibr8-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19941215)74:12<3083::AID-CNCR2820741204>3.0.CO;2-7"},{"key":"bibr9-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870020082022"},{"key":"bibr10-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199605000-00004"},{"key":"bibr11-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989670222-X"},{"key":"bibr12-000348949710600716","first-page":"1701","volume":"142","author":"Burke AP","year":"1993","journal-title":"Am J Pathol"},{"key":"bibr13-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5258.115"},{"key":"bibr14-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1038\/362359a0"},{"key":"bibr15-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.3.772"},{"key":"bibr16-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1159\/000163649"},{"key":"bibr17-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112491"},{"key":"bibr18-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(90)90081-Z"},{"key":"bibr19-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.18.7998"},{"key":"bibr20-000348949710600716","first-page":"36","volume":"119","author":"Burke AP","year":"1995","journal-title":"Arch Pathol Lab Med"},{"key":"bibr21-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(94)90196-1"},{"key":"bibr22-000348949710600716","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90247-5"},{"key":"bibr23-000348949710600716","unstructured":"\u00d6st \u00c5, Baroni CD, Biberfeld P, Lymphadenopathy in HIV infection: Histological classification and staging. 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