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Even if the two areas have different embryological derivations, there is no anatomic evidence of a \u201cbarrier\u201d that could prevent supraglottic cancer from extending downward to the glottis. Numerous adequate pathologic studies, including whole organ sections, confirm that for advanced cancers, anatomic compartments delimiting the spread of the neoplastic process from the supraglottis to the glottis do not exist. Therefore, supraglottic laryngectomy should be performed not on the basis of embryological considerations, but on the basis of the actual extension of the neoplastic lesion.<\/jats:p>","DOI":"10.1177\/000348949710600820","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T14:38:05Z","timestamp":1412347085000},"page":"716-719","source":"Crossref","is-referenced-by-count":8,"title":["Clinicopathological Consultation Barrier between the Supraglottis and the Glottis: Myth or Reality?"],"prefix":"10.1177","volume":"106","author":[{"given":"Alfio","family":"Ferlito","sequence":"first","affiliation":[{"name":"Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Olofsson","sequence":"additional","affiliation":[{"name":"Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Rinaldo","sequence":"additional","affiliation":[{"name":"Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1997,8,1]]},"reference":[{"key":"bibr1-000348949710600820","first-page":"156","volume":"44","author":"Frazier EJ","year":"1909","journal-title":"J Anat Physiol"},{"key":"bibr2-000348949710600820","first-page":"412","volume":"3","author":"Hast MH","year":"1974","journal-title":"Can J Otolaryngol"},{"key":"bibr3-000348949710600820","doi-asserted-by":"publisher","DOI":"10.1177\/000348946807700602"},{"key":"bibr4-000348949710600820","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197509000-00014"},{"key":"bibr5-000348949710600820","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-71100-8"},{"key":"bibr6-000348949710600820","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000401"},{"key":"bibr7-000348949710600820","first-page":"6","volume-title":"Laryngeal cancer","author":"Kirchner JA","year":"1991"},{"key":"bibr8-000348949710600820","first-page":"431","volume-title":"Management of head and neck cancer. 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