{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:12:51Z","timestamp":1777443171602,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["KMU-M113013"],"award-info":[{"award-number":["KMU-M113013"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC113-2113-M-037-006"],"award-info":[{"award-number":["NSTC113-2113-M-037-006"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC113-2113-M-037-009"],"award-info":[{"award-number":["NSTC113-2113-M-037-009"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC113-2113-M-037-015"],"award-info":[{"award-number":["NSTC113-2113-M-037-015"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Appl Spectrosc"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>\n                    This study developed a dual-readout system utilizing fluorescence and colorimetry based on iron oxide quantum dots (IO-QDs) for detecting tetracycline (TCy). IO-QDs were synthesized within 6\u2005h using L-leucine as a surface modifier, achieving a more efficient route. Upon interaction with TCy, IO-QDs exhibited a significant decrease in fluorescence response and observable color changes, while fluorescence lifetime remained consistent regardless of TCy presence. Moreover, IO-QDs\u2019 fluorescence response remained stable across various temperatures. The F\u00f6rster resonance energy transfer distance of less than 2\u2005nm and a quenching constant of 2.90\u2009\u00d7\u200910\n                    <jats:sup>12<\/jats:sup>\n                    \u2005M\n                    <jats:sup>\u20131<\/jats:sup>\n                    s\n                    <jats:sup>\u20131<\/jats:sup>\n                    indicated static quenching in the presence of TCy. Additionally, significant changes in observed and corrected fluorescence efficiency suggested the involvement of the inner filter effect in the fluorescence quenching of IO-QDs. The synthesized IO-QDs were then utilized for selective and rapid fluorescence-based TCy detection, showing a linear range of 0.5 to 80\u2005\u03bcM. Simultaneously, a colorimetric method for TCy detection was established, demonstrating a good linear relationship within the range of 0.5 to 20\u2005\u03bcM. The detection limits for TCy were determined as 0.539 and 0.329\u2005\u03bcM using fluorescence and colorimetric approaches, respectively. Furthermore, IO-QDs were applied to detect real samples, and the dual-readout probe exhibited satisfactory recoveries, confirming the practical reliability of the developed method for analyzing milk and drinking water samples.\n                  <\/jats:p>","DOI":"10.1177\/00037028241279464","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T15:41:02Z","timestamp":1727106062000},"page":"1191-1202","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Fluorescence and Colorimetric Dual-Readout Detection of Tetracycline Using Leucine-Conjugated Iron Oxide Quantum Dots"],"prefix":"10.1177","volume":"78","author":[{"given":"Sri","family":"Sudewi","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Faculty of Mathematics and Natural Science, Universitas Sam Ratulangi, Manado, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penki Venkata Sai","family":"Sashank","sequence":"additional","affiliation":[{"name":"Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1856-7681","authenticated-orcid":false,"given":"Akhtar","family":"Rasool","sequence":"additional","affiliation":[{"name":"Research Center for Chemistry, National Research and Innovation Agency (BRIN), Tangerang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najeeb","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Zulfajri","sequence":"additional","affiliation":[{"name":"Department of Chemistry Education, Universitas Serambi Mekkah, Banda Aceh, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsuan-Ying","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2241-1954","authenticated-orcid":false,"given":"Genin Gary","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung"},{"name":"Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung"},{"name":"Department of Chemistry, National Sun Yat-Sen University, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"bibr1-00037028241279464","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.0c01890"},{"key":"bibr2-00037028241279464","doi-asserted-by":"publisher","DOI":"10.1039\/c0ay00511h"},{"issue":"890","key":"bibr3-00037028241279464","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1136\/pgmj.75.890.751","volume":"75","author":"Kashyap A.S.","year":"1999","journal-title":"Postgrad. 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