{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:32:17Z","timestamp":1777433537110,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2001,9,1]],"date-time":"2001-09-01T00:00:00Z","timestamp":999302400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[2001,9]]},"abstract":"<jats:p>The reliability of a recently released total bilirubin assay for a blood gas analyser was assessed in two Australian hospital laboratories. The instrument computes total bilirubin concentration from multi-wavelength absorbance measurements of undiluted whole blood or plasma. Performance of the Radiometer ABL 735 blood gas analyser bilirubin method (software version 3.6) was compared with a proven Roche diazo method for Hitachi analysers, calibrated using primary standards prepared from NIST SRM 916a bilirubin. Acceptable bilirubin results were found over a wide concentration range for most neonatal samples of whole blood or plasma. For adult specimens, bilirubin results were approximately 10% lower on the blood gas analyser. Within-run imprecision (whole blood) was &lt;2\u00b75%, between-day imprecision (synthetic controls) &lt;1\u00b70%, and the bilirubin assay for both whole blood and plasma was linear to 1000\u03bcmol\/L. Using sampling options from 35 \u03bcL to 195\u03bcL, bilirubin results differed by less than 3%, with a 95 \u03bcL syringe option producing the highest results. We conclude that the Radiometer ABL 735 bilirubin assay is suitable for near-patient assessment of neonatal jaundice using whole blood, thus eliminating the need for sample centrifugation. Verification using laboratory methods can be used when required. A positive correction of approximately 10% is required for adult specimens to conform with Hitachi results (SRM 916a calibration), possibly due to the optical characteristics of the higher proportion of conjugated bilirubin and other substances present in most adult samples.<\/jats:p>","DOI":"10.1177\/000456320103800511","type":"journal-article","created":{"date-parts":[[2014,2,5]],"date-time":"2014-02-05T16:51:35Z","timestamp":1391619095000},"page":"533-540","source":"Crossref","is-referenced-by-count":15,"title":["Bilirubin Measured on a Blood Gas Analyser: A Suitable Alternative for Near-Patient Assessment of Neonatal Jaundice?"],"prefix":"10.1177","volume":"38","author":[{"given":"Michael","family":"Peake","sequence":"first","affiliation":[{"name":"Routine Biochemistry, SouthPath, Flinders Medical Centre, Bedford Park, South Australia 5042"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beryl","family":"Mazzachi","sequence":"additional","affiliation":[{"name":"Routine Biochemistry, SouthPath, Flinders Medical Centre, Bedford Park, South Australia 5042"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Fudge","sequence":"additional","affiliation":[{"name":"Routine Biochemistry, SouthPath, Flinders Medical Centre, Bedford Park, South Australia 5042"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renze","family":"Bais","sequence":"additional","affiliation":[{"name":"Express Laboratory, Pacific Laboratory Medicine Services, Royal North Shore Hospital, St Leonards, NSW 2065, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,9,1]]},"reference":[{"key":"bibr1-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.4.599"},{"key":"bibr2-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9120(96)00131-2"},{"key":"bibr3-000456320103800511","volume-title":"Measuring bilirubin on whole blood","author":"Fussing I.","year":"2000"},{"key":"bibr4-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/31.11.1779"},{"key":"bibr5-000456320103800511","first-page":"S95","volume":"41","author":"Schlebusch H","year":"1995","journal-title":"Clin Chem"},{"key":"bibr6-000456320103800511","first-page":"73","volume":"16","author":"Mazzachi BC","year":"1995","journal-title":"Clin Biochem Revs"},{"key":"bibr7-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199904020-01683"},{"key":"bibr8-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/32.3.470"},{"key":"bibr9-000456320103800511","first-page":"709","volume":"21","author":"Passing H","year":"1983","journal-title":"J Clin Chem Clin Biochem"},{"key":"bibr10-000456320103800511","first-page":"783","volume":"26","author":"Bablok W","year":"1988","journal-title":"J Clin Chem Clin Biochem"},{"key":"bibr11-000456320103800511","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"bibr12-000456320103800511","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1542\/peds.94.4.558","volume":"94","author":"American Academy of Pediatrics","year":"1994","journal-title":"Pediatrics"},{"key":"bibr13-000456320103800511","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/clinchem\/42.6.869","volume":"42","author":"Vreman HJ","year":"1996","journal-title":"Clin Chem"},{"key":"bibr14-000456320103800511","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1093\/clinchem\/42.6.845","volume":"42","author":"Doumas BT","year":"1996","journal-title":"Clin Chem"}],"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000456320103800511","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000456320103800511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:51:31Z","timestamp":1777377091000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000456320103800511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["10.1177\/000456320103800511"],"URL":"https:\/\/doi.org\/10.1177\/000456320103800511","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}