{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:05:47Z","timestamp":1777428347356,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1990,3,1]],"date-time":"1990-03-01T00:00:00Z","timestamp":636249600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Biochem"],"published-print":{"date-parts":[[1990,3]]},"abstract":"<jats:p>Urine samples collected from four patients with a mucopolysaccharide storage disease (MPS) and two non-MPS patients were distributed to up to 33 laboratories as a test of their ability to detect abnormal glycosaminoglycan excretion. Seven national reference laboratories made a correct diagnostic assignment to all samples analysed. Qualitative turbidity and spot tests were shown to be unreliable. Failure to identify the excretion pattern occurred when reliance was placed on one-dimensional electrophoresis or thin layer chromatography as the sole method for glycosaminoglycan identification. Two-dimensional electrophoresis appeared to be the method of choice provided that staff had adequate experience in interpretation. Clinically unacceptable delays in analysis were common, with 80% of laboratories taking longer than 10 days to issue a report.<\/jats:p>","DOI":"10.1177\/000456329002700208","type":"journal-article","created":{"date-parts":[[2014,2,5]],"date-time":"2014-02-05T16:58:39Z","timestamp":1391619519000},"page":"133-138","source":"Crossref","is-referenced-by-count":8,"title":["Results of a Quality Assurance Exercise for Urinary Glycosaminoglycan Excretion"],"prefix":"10.1177","volume":"27","author":[{"given":"Angela","family":"Brimble","sequence":"first","affiliation":[{"name":"Department of Paediatric Chemical Pathology, Bristol Maternity Hospital, Southwell Street, Bristol BS2 8EG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Pennock","sequence":"additional","affiliation":[{"name":"Department of Paediatric Chemical Pathology, Bristol Maternity Hospital, Southwell Street, Bristol BS2 8EG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Stone","sequence":"additional","affiliation":[{"name":"Department of Paediatric Chemical Pathology, Bristol Maternity Hospital, Southwell Street, Bristol BS2 8EG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,3,1]]},"reference":[{"key":"bibr1-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(68)90205-4"},{"key":"bibr2-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(71)90460-X"},{"key":"bibr3-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(77)90466-1"},{"key":"bibr4-000456329002700208","first-page":"136","volume":"55","author":"Berry HK","year":"1960","journal-title":"J Clin Lab Med"},{"key":"bibr5-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1136\/adc.37.195.505"},{"key":"bibr6-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5291.1555-d"},{"key":"bibr7-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1136\/adc.41.215.91"},{"key":"bibr8-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196602172740705"},{"key":"bibr9-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.41.9.936"},{"key":"bibr10-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1042\/bj1310343"},{"key":"bibr11-000456329002700208","author":"Pennock CA","year":"1980","journal-title":"A C P Broadsheet"},{"key":"bibr12-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(62)90095-7"},{"key":"bibr13-000456329002700208","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(72)90287-2"}],"container-title":["Annals of Clinical Biochemistry: International Journal of Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000456329002700208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000456329002700208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:36:03Z","timestamp":1777376163000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000456329002700208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,3]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,3]]}},"alternative-id":["10.1177\/000456329002700208"],"URL":"https:\/\/doi.org\/10.1177\/000456329002700208","relation":{},"ISSN":["0004-5632","1758-1001"],"issn-type":[{"value":"0004-5632","type":"print"},{"value":"1758-1001","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,3]]}}}