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<jats:title>Background:<\/jats:title>\n                    <jats:p>The Research Domain Criteria seeks to bridge knowledge from neuroscience with clinical practice by promoting research into valid neurocognitive phenotypes and dimensions, irrespective of symptoms and diagnoses as currently conceptualized. While the Research Domain Criteria offers a vision of future research and practice, its 39 functional constructs need refinement to better target new phenotyping efforts. This study aimed to determine which Research Domain Criteria constructs are most relevant to understanding obsessive-compulsive and related disorders, based on a consensus between experts in the field of obsessive-compulsive and related disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Based on a modified Delphi method, 46 experts were recruited from Australia, Africa, Asia, Europe and the Americas. Over three rounds, experts had the opportunity to review their opinion in light of feedback from the previous round, which included how their response compared to other experts and a summary of comments given.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Thirty-four experts completed round one, of whom 28 (82%) completed round two and 24 (71%) completed round three. At the final round, four constructs were endorsed by \u2a7e75% of experts as \u2018primary constructs\u2019 and therefore central to understanding obsessive-compulsive and related disorders. Of these constructs, one came from the Positive Valence System (Habit), two from the Cognitive Control System (Response Selection\/Inhibition and Performance Monitoring) and the final construct was an additional item suggested by experts (Compulsivity).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study identified four Research Domain Criteria constructs that, according to experts, cut across different obsessive-compulsive and related disorders. These constructs represent key areas for future investigation, and may have potential implications for clinical practice in terms of diagnostic processes and therapeutic management of obsessive-compulsive and related disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0004867420912327","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T09:32:50Z","timestamp":1588584770000},"page":"719-731","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["A transdiagnostic perspective of constructs underlying obsessive-compulsive and related disorders: An international Delphi consensus study"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9075-8226","authenticated-orcid":false,"given":"Leonardo F","family":"Fontenelle","sequence":"first","affiliation":[{"name":"Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia"},{"name":"D\u2019Or Institute for Research and Education, D\u2019Or S\u00e3o Luiz Network, Rio de Janeiro, Brazil"},{"name":"Obsessive, Compulsive, and Anxiety Spectrum Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Oldenhof","sequence":"additional","affiliation":[{"name":"Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Eduarda Moreira-de-Oliveira","sequence":"additional","affiliation":[{"name":"D\u2019Or Institute for Research and Education, D\u2019Or S\u00e3o Luiz Network, Rio de Janeiro, Brazil"},{"name":"Obsessive, Compulsive, and Anxiety Spectrum Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan S","family":"Abramowitz","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin M","family":"Antony","sequence":"additional","affiliation":[{"name":"Department of Psychology, Ryerson University, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Cath","sequence":"additional","affiliation":[{"name":"RGOc and Department of Psychiatry, Rijksuniversity Groningen, UMC Groningen, Groningen, The Netherlands"},{"name":"Department of Specialized Trainings, Mental Health Services Drenthe, Assen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Carter","sequence":"additional","affiliation":[{"name":"Turner Institute for Brain and 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(CIBERSAM) and Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6772-6995","authenticated-orcid":false,"given":"Vladan","family":"Starcevic","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Nepean Hospital, Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, The University of Sydney, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan J","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and MRC Unit on Risk & Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail","family":"Steketee","sequence":"additional","affiliation":[{"name":"School of Social Work, Boston University, Boston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A","family":"Storch","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The University of British Columbia, Vancouver, BC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odile A","family":"van den Heuvel","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Department of Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands"},{"name":"Bergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Veale","sequence":"additional","affiliation":[{"name":"South London and Maudsley NHS Foundation Trust, Institute of 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