{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:46:30Z","timestamp":1793411190079,"version":"4.5.0"},"reference-count":74,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Aust N Z J Psychiatry"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To provide a qualitative view and quantitative measure of sleep disturbances across and between early stages \u2013 clinical ultra high-risk and first episode \u2013 of psychotic and bipolar disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Electronic databases (PubMed, Cochrane, Embase, PsychINFO) were searched up to March 2021 for studies comparing sleep measures between individuals with an early stage and controls. Standard mean deviations (Cohen\u2019s d effect sizes) were calculated for all comparisons and pooled with random-effects models. Chi-square tests were used for direct between-subgroups (ultra high-risk vs first episode) comparisons of standard mean deviations. The effects of age, sex ratio, symptoms and treatment were examined in meta-regression analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A database search identified 13 studies that contrasted sleep measures between individuals with an early stage ( N\u2009=\u2009537) and controls ( N\u2009=\u2009360). We observed poorer subjective sleep quality (standard mean deviation\u2009=\u20091.32; 95% confidence interval, [1.01, 1.62]), shorter total sleep time (standard mean deviation\u2009=\u22120.44; 95% confidence interval, [\u22120.67, \u22120.21]), lower sleep efficiency (standard mean deviation\u2009=\u2009\u22120.72; 95% confidence interval, [\u22121.08, \u22120.36]), longer sleep onset latency (standard mean deviation\u2009=\u20090.75; 95% confidence interval, [0.45, 1.06]) and longer duration of wake after sleep onset (standard mean deviation\u2009=\u20090.49; 95% confidence interval, [0.21, 0.77]) were observed in early stages compared to controls. No significant differences were observed for any of the reported electroencephalographic parameters of sleep architecture. No significant between-subgroups differences were observed. Meta-regressions revealed a significant effect of the age and the antipsychotic status on subjective measures of sleep.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The early stage population presents with significant impairments of subjective sleep quality continuity, duration and initiation. Systematic assessments of sleep in early intervention settings may allow early identification and treatment of sleep disturbances in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00048674211068395","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T12:22:45Z","timestamp":1640953365000},"page":"1068-1079","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Sleep disturbances in early clinical stages of psychotic and bipolar disorders: A meta-analysis"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5121-8769","authenticated-orcid":false,"given":"Cl\u00e9ment","family":"Dond\u00e9","sequence":"first","affiliation":[{"name":"Univ. 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Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Adult Psychiatry Department, Grenoble Institut Neurosciences, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Tamisier","sequence":"additional","affiliation":[{"name":"Univ. Grenoble Alpes, INSERM, CHU Grenoble Alpes, HP2, Pneumology and Physiology Department, Thorax and vessels pole, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Lejoyeux","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Psychiatry and Addictology Department, AP-HP, GHU Paris Nord, DMU Neurosciences, Bichat Hospital \u2013 Claude Bernard, GHU Paris \u2013 Psychiatry & Neurosciences, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pia","family":"d\u2019Ortho","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, NeuroDiderot, Inserm U1141, Sleep Medicine and Clinical Physiology Department, AP-HP, GHU Paris Nord, DMU DREAM, Bichat Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mircea","family":"Polosan","sequence":"additional","affiliation":[{"name":"Univ. 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