{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:11:49Z","timestamp":1792023109870,"version":"4.4.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Aust N Z J Psychiatry"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Adolescent depression is a significant public health concern, with prevalence rates increasing globally over recent years. Mobile-based cognitive behavioural therapy applications are increasingly used to address adolescent depression, but their effectiveness remains unclear. This study evaluated the impact of mobile-based cognitive behavioural therapy apps on depressive symptoms in this population, with secondary analyses examining anxiety, quality of life, usability and adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      A systematic review identified 10 randomized controlled trials containing 1896 participants. These studies were published since 2014 and assessed the effects of mobile-based cognitive behavioural therapy for depression in adolescents (aged 13\u201325\u2009years). Databases searched included MEDLINE, PsycINFO, Embase, PubMed and the Cochrane Library. Subsequent meta-analysis was conducted on nine studies (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20091127). Studies reporting depressive symptom outcomes were included in meta-analyses using a random-effects model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Meta-analysis showed a significant reduction in depressive symptoms compared with the control groups (Cohen\u2019s\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u2009\u22120.24; 95% confidence interval\u2009=\u2009[\u22120.36, \u22120.13],\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with negligible heterogeneity (\n                      <jats:italic toggle=\"yes\">I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%). Meta-regression showed no significant association between follow-up duration and effect size. No significant effects were found for anxiety (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u2009\u22120.16), but improvements were observed in quality of life (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.37) and usability (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.37). Adverse event rates were lower in the intervention groups (risk ratio\u2009=\u20090.68).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Mobile-based cognitive behavioural therapy is a moderately effective short-term intervention for adolescent and young adult depression. These findings support its integration into mental health service delivery, although strategies to sustain long-term benefits are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00048674261439533","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T04:27:11Z","timestamp":1776227231000},"page":"633-642","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of mobile-based cognitive behavioural therapy for adolescent depression: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5902-2974","authenticated-orcid":false,"given":"Aditya","family":"Sathe","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Eastern Health, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhir","family":"Nainani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Austin Health, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6963-7307","authenticated-orcid":false,"given":"Ahmed","family":"Elaraby","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Eastern Health, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Lowe","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Eastern Health, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/532020a"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2024.104554"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.2196\/47860"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/15374410701817865"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.7332"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-10-113"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.2196\/40719"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12663"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.01.009"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.150268"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-022-00677-8"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.4364"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1745691610393527"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdgth.2023.1062471"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867415617836"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.2196\/25847"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20673"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.1967"},{"key":"e_1_3_3_20_1","article-title":"Mobile apps to reduce depressive symptoms and alcohol use in youth: A systematic review and meta-analysis: A systematic review","volume":"20","author":"Magwood O","year":"2024","unstructured":"Magwood O, et al. (2024) Mobile apps to reduce depressive symptoms and alcohol use in youth: A systematic review and meta-analysis: A systematic review. Campbell Syst Rev 20: e1398.","journal-title":"Campbell Syst Rev"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.2196\/45186"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.2196\/40242"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.13294"},{"key":"e_1_3_3_24_1","article-title":"The MobiliseMe study: A randomised controlled efficacy trial of a cognitive behavioural therapy smartphone application (ClearlyMe\u00ae) for reducing depressive symptoms in adolescents","author":"O\u2019Dea B","year":"2024","unstructured":"O\u2019Dea B, et al. (2024) The MobiliseMe study: A randomised controlled efficacy trial of a cognitive behavioural therapy smartphone application (ClearlyMe\u00ae) for reducing depressive symptoms in adolescents. medRxiv, 11.17.24317363, 2024.","journal-title":"medRxiv"},{"key":"e_1_3_3_25_1","volume-title":"Project STAND (Self-guided Treatment for Adolescents Navigating Depression): A randomized controlled trial","author":"Padmanabhan A","year":"2024","unstructured":"Padmanabhan A, et al. (2024) Project STAND (Self-guided Treatment for Adolescents Navigating Depression): A randomized controlled trial, 12 June. Palo Alto, CA: Limbix Health, Inc."},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.2196\/48467"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(18)30022-1"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjc.12333"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chc.2011.01.012"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-087342"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20883"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-49"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.2196\/29842"}],"container-title":["Australian &amp; New Zealand Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00048674261439533","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00048674261439533","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00048674261439533","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T11:50:17Z","timestamp":1782474617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00048674261439533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,14]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1177\/00048674261439533"],"URL":"https:\/\/doi.org\/10.1177\/00048674261439533","relation":{},"ISSN":["0004-8674","1440-1614"],"issn-type":[{"value":"0004-8674","type":"print"},{"value":"1440-1614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,14]]}}}