{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:05:52Z","timestamp":1791353152065,"version":"4.3.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:p>The simultaneous occurrence of juvenile dermatomyositis (JDMS) and diabetes mellitus is described in 2 pediatric patients. Both these patients presented with significant weight loss, polyuria, and polydypsia within a short time of being diagnosed with JDMS, while these patients were taking oral prednisone (40-60 mg\/day in divided doses). Laboratory evaluation detected ketonuria, significant hyperglycemia (696 and 913mg\/d L) and low serum levels of insulin and Cpeptide. Both these patients were treated with high doses of insulin. Islet cell and GAD65 antibodies were found to be positive in 1 of the patients, pointing toward a diagnosis of insulin-dependent diabetes mellitus. The other patient tested negative for these antibodies and required insulin therapy for approximately 6 months. Steroid-induced diabetes mellitus seemed highly likely in this case. We hypothesize that a common environmental trigger possibly a viral infection might have been responsible in causing 2 different autoimmune pathologies in these genetically predisposed individuals.<\/jats:p>","DOI":"10.1177\/000992280304200514","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:21:41Z","timestamp":1182460901000},"page":"459-462","source":"Crossref","is-referenced-by-count":9,"title":["Simultaneous Occurrence of Diabetes Mellitus and Juvenile Dermatomyositis: Report of Two Cases"],"prefix":"10.1177","volume":"42","author":[{"given":"Ranju","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Cuchacovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis R.","family":"Espinoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Gedalia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Medicine, LSU Health Sciences Center and Children's Hospital, New Orleans, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2003,6,1]]},"reference":[{"key":"atypb1","first-page":"631","volume":"109","author":"Calas E","year":"1972","journal-title":"Mars Med"},{"key":"atypb2","first-page":"143","volume":"9","author":"Kosik VN.","year":"1969","journal-title":"Vrach Delo"},{"key":"atypb3","first-page":"147","volume":"99","author":"Huang Yong-qi","year":"1986","journal-title":"Chinese Med J"},{"key":"atypb4","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/rheumatology\/27.2.146","volume":"27","author":"Sattar MA","year":"1988","journal-title":"Br J Rheumato L"},{"key":"atypb5","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/art.1780380403","volume":"38","author":"Beher SM","year":"1995","journal-title":"Arthr Rheum"},{"key":"atypb6","first-page":"715","volume":"48","author":"Medsger TA","year":"1970","journal-title":"Am JMed"},{"key":"atypb7","first-page":"S24","volume":"26","author":"Christensen ML","year":"1983","journal-title":"Arthr Rheum"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780291109"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/BF02231595"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780380518"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1978.03280370055026"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1136\/ard.49.5.310"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780381019"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1007\/BF00401138"},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1172\/JCI117567","volume":"94","author":"Hyoty H","year":"1994","journal-title":"J Clin Invest"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)90001-6"},{"key":"atypb17","first-page":"1226","volume":"17","author":"Varga J","year":"1990","journal-title":"JRheum"},{"key":"atypb18","first-page":"610","volume":"28","author":"Huemer C","year":"2001","journal-title":"JRheumatol"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111141"},{"key":"atypb20","first-page":"191","volume":"42","author":"Gunnerson R","year":"1977","journal-title":"Scand J Urol Nephrol"},{"key":"atypb21","first-page":"191","volume":"42","author":"Reaven GM.","year":"1988","journal-title":"Diabetes"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992280304200514","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992280304200514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:26:18Z","timestamp":1777393578000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992280304200514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["10.1177\/000992280304200514"],"URL":"https:\/\/doi.org\/10.1177\/000992280304200514","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}