{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T11:39:41Z","timestamp":1779881981364,"version":"3.53.1"},"reference-count":13,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:p>In this study, the clinical and laboratory features of children with lymphadenopathy were evaluated. Over a 3-year period, 126 patients were referred to the clinic for lymphadenopathy. Twenty-eight of cases have diseases mimicking lymphadenopathy; 98 (mean age: 86 \u00b1 55 months) have lymphadenopathy. Localized, limited, and generalized involvement was found in 52%, 30%, and 18% of patients. The most common localization was the head and neck region. The causes of lymphadenopathy were benign diseases in 75 patients. Sixty percent were reactive lymphadenopathy, 39% were lymphadenitis. Lymphadenitis was more frequently localized and bigger than 3 cm compared with reactive adenopathy (p = .02, p = .004). Twenty-three patients have malignant diseases whose mean age was higher than others (p = .002). The enlargement of supraclavicular nodes was more likely due to malignant disease (p = .001). The risk of malignant disease was higher in patients who had generalized lymphadenopathy, lymph nodes bigger than 3 cm, hepatosplenomegaly, and high lactate dehydrogenase levels. In conclusion, this study pointed out the important clues for the differential diagnosis, which were present in the history, physical, and laboratory findings.<\/jats:p>","DOI":"10.1177\/0009922806290609","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:21:41Z","timestamp":1182460901000},"page":"544-549","source":"Crossref","is-referenced-by-count":50,"title":["Analysis of Children with Peripheral Lymphadenopathy"],"prefix":"10.1177","volume":"45","author":[{"given":"Nilgun","family":"Yaris","sequence":"first","affiliation":[{"name":"Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Cakir","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emin","family":"S\u00f6zen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umit","family":"Cobanoglu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1177\/000992280404300104"},{"key":"atypb2","first-page":"1313","volume":"58","author":"Ferrer R.","year":"1998","journal-title":"Am Fam Physician"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5245(03)00212-8"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(92)90004-D"},{"key":"atypb5","first-page":"449","volume":"20","author":"Fitjen GH","year":"1985","journal-title":"J Fam Pract"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1177\/000992288302200703"},{"key":"atypb7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0065-3101(22)00645-4","volume":"28","author":"Bedros AA.","year":"1981","journal-title":"Adv Pediatr"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-002-0771-x"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1542\/peds.69.4.391","volume":"69","author":"Knight PJ","year":"1982","journal-title":"Pediatrics"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1080\/088800199276813"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1080\/08880010252899361"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(99)90101-X"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/99.4.385"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922806290609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922806290609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:26:40Z","timestamp":1777393600000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0009922806290609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["10.1177\/0009922806290609"],"URL":"https:\/\/doi.org\/10.1177\/0009922806290609","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7]]}}}