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Two recently developed vaccines (RotaTeq [rotavirus vaccine, live, oral, pentavalent], and Rotarix [rotavirus vaccine, live]) share some characteristics of an ideal rotavirus vaccine. High efficacy, excellent tolerability, and no increased risk of intussusception were shown in separate clinical trials of more than 60000 infants for each trial, as well as in smaller phase 3 clinical trials of each vaccine. Vaccination against rotavirus will substantially reduce rotavirus gastroenteritis-associated morbidity and mortality and, in so doing, bring about a significant reduction in rotavirus gastroenteritis-associated healthcare utilization.<\/jats:p>","DOI":"10.1177\/0009922808314903","type":"journal-article","created":{"date-parts":[[2008,5,8]],"date-time":"2008-05-08T21:45:14Z","timestamp":1210283114000},"page":"555-563","source":"Crossref","is-referenced-by-count":3,"title":["Characteristics of an Ideal Rotavirus Vaccine"],"prefix":"10.1177","volume":"47","author":[{"given":"Keith S.","family":"Reisinger","sequence":"first","affiliation":[{"name":"Primary Physicians Research, Pittsburgh, Pennsylvania, , Kentucky Pediatric\/Adult Research, Bardstown, Kentucky"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stan L.","family":"Block","sequence":"additional","affiliation":[{"name":"Primary Physicians Research, Pittsburgh, Pennsylvania, Kentucky Pediatric\/Adult Research, Bardstown, Kentucky"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0404.980406"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1202.050006"},{"issue":"12","key":"atypb3","first-page":"1","volume":"55","author":"Parashar UD","year":"2006","journal-title":"Recommendations of the Advisory Committee on Immunization Practices (ACIP). 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