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The case of a 9-year-old boy with autism was recently described, who was hospitalized because of pain in the right hip, refusal to walk, fatigue, irritability, skin rash, and subsequent gingival swelling after an unspecified upper respiratory illness. The boy was diagnosed with scurvy. However, the gingival symptoms occurred after treatment with indomethacin, which lowers vitamin C levels; severe bone pain and fatigue are also well-documented symptoms of hypervitaminosis A. This review of a case report of a boy with autism provides an opportunity to present a new hypothesis of the mechanism of these postinfection symptoms in the context of an increasingly common condition of childhood.<\/jats:p>","DOI":"10.1177\/0009922808320697","type":"journal-article","created":{"date-parts":[[2008,6,19]],"date-time":"2008-06-19T21:53:24Z","timestamp":1213912404000},"page":"21-25","source":"Crossref","is-referenced-by-count":4,"title":["Bone Pain, Growth Failure, and Skin Rash After an Upper Respiratory Illness in a Boy with Autism: Possible Association with Altered Retinoid Metabolism"],"prefix":"10.1177","volume":"48","author":[{"given":"Anthony R.","family":"Mawson","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi, amawson@ prevmed.umsmed.edu"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,7,22]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.27-5-170"},{"key":"atypb2","first-page":"164","volume":"27","author":"Bueso MB","year":"2006","journal-title":"Allergy Asthma Proc"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.1.e3"},{"key":"atypb4","first-page":"32","volume":"2","author":"Chi ZC","year":"2003","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc079017"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.e55"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gal092"},{"key":"atypb8","volume-title":"Vitamin A: Vitamins and Hormones; vol 75","author":"Litwak G","year":"2007"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2005.03.002"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/83.2.191"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2000.tb01848.x"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690230041007"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3180340a06"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/6.4.335"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(00)00262-6"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.10.1899"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1984.55.8.474"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2005.tb00064.x"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2007.02.002"},{"key":"atypb20","first-page":"423","volume":"67","author":"Barua AR","year":"1997","journal-title":"Int J Vitam Nutr Res"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.46.Suppl_S113"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/68.5.1088"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1097\/00075197-200111000-00002"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M600528-JLR200"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(04)73243-9"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.113714"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.3.392"},{"key":"atypb28","unstructured":"Food and Nutrition Board, Institute of Medicine. 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