{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:59:56Z","timestamp":1777525196734,"version":"3.51.4"},"reference-count":57,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,1,20]],"date-time":"2010-01-20T00:00:00Z","timestamp":1263945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>\n                    Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia in the United States. Vaccines directed against meningococcal disease must elicit high and persistent titers of bactericidal antibodies against prevalent meningococcal serogroups and be highly efficacious in preventing meningococcal infection. Currently, 2 quadrivalent (A, C, W-135, Y) vaccines\u2014a polysaccharide meningococcal vaccine and a conjugate meningococcal vaccine\u2014are licensed in the United States. Neither is approved for use in infants or toddlers younger than 2 years of age. Results of studies with an investigational quadrivalent (ACWY) meningococcal CRM\n                    <jats:sub>197<\/jats:sub>\n                    glycoconjugate vaccine in infants demonstrate that this vaccine has potential to protect this age group. The availability of an effective vaccine for routine universal infant immunization is particularly important because the incidence of invasive meningococcal disease is greatest in infants for all serogroups and because achievable vaccination rates are much greater for infants and young children than they are for adolescents.\n                  <\/jats:p>","DOI":"10.1177\/0009922809354327","type":"journal-article","created":{"date-parts":[[2010,1,20]],"date-time":"2010-01-20T20:49:57Z","timestamp":1264020597000},"page":"586-597","source":"Crossref","is-referenced-by-count":8,"title":["Optimizing Protection Against Meningococcal Disease"],"prefix":"10.1177","volume":"49","author":[{"given":"Keith S.","family":"Reisinger","sequence":"first","affiliation":[{"name":"Primary Physicians Research, Pittsburgh, PA, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Black","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey J.","family":"Stoddard","sequence":"additional","affiliation":[{"name":"Novartis Vaccines and Diagnostics, Cambridge, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,1,20]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022823"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199710023371404"},{"issue":"7","key":"atypb3","first-page":"1","volume":"54","author":"Bilukha OO","year":"2005","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S962"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105033441807"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp048246"},{"key":"atypb7","volume-title":"The Changing Epidemiology of Meningococcal Disease Among US Children, Adolescents and Young Adults","author":"Schaffner W.","year":"2004"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1086\/315158"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1086\/520303"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.20.1906"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.16.1493"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000147642.85129.05"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.5.6.851"},{"key":"atypb14","volume-title":"Active bacterial core surveillance (ABCs). Neisseria meningitidis surveillance reports 1997-2007","author":"Centers for Disease Control and Prevention.","year":"2009"},{"key":"atypb15","volume-title":"Factsheet: meningococcal diseases and meningococcal vaccines; April 25, 2006","author":"Centers for Disease Control and Prevention.","year":"2009"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2514"},{"key":"atypb17","unstructured":"Steinhoff MC Global epidemiology of meningococcal infections. In: Nelson KE, Masters Williams C, eds. Infectious Disease Epidemiology: Theory and Practice. 2nd ed. Boston, MA: Jones & Bartlett ; 2007:637-652."},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.1.142-164.2006"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31818e037d"},{"key":"atypb20","first-page":"6","volume":"1","author":"Leimkugel J.","year":"2009","journal-title":"J Bacteriol."},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1086\/509619"},{"key":"atypb22","first-page":"462","volume":"57","author":"Centers for Disease Control and Prevention.","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(01)00209-2"},{"key":"atypb24","first-page":"217","volume":"299","author":"Harrison LH","year":"2008","journal-title":"N Engl J Med"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.4161\/hv.4513"},{"key":"atypb26","volume-title":"Paper presented at: European Society for Paediatric Infectious Diseases (ESPID) Annual Meeting","author":"Miller E."},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.4161\/hv.4.2.4871"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16725-1"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.14.1668"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92719-V"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08679-8"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1086\/344324"},{"key":"atypb33","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7385.365"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1086\/527401"},{"key":"atypb35","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.1.3.399"},{"key":"atypb36","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000126297.28952.f8"},{"key":"atypb37","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03594-7"},{"key":"atypb38","volume-title":"Paper presented at: 2008 Pediatric Academic Society Annual Meeting","author":"Jackson L."},{"key":"atypb39","doi-asserted-by":"publisher","DOI":"10.1086\/345763"},{"key":"atypb40","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.159.10.907"},{"key":"atypb41","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000148928.10057.86"},{"key":"atypb42","volume-title":"Paper presented at: 45th Annual Meeting of IDSA; October 4-7, 2007","author":"Jackson LA"},{"key":"atypb43","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31818a0237"},{"key":"atypb44","volume-title":"Paper presented at: 45th Annual Meeting of IDSA","author":"Black S."},{"key":"atypb45","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2007.29-c"},{"key":"atypb46","volume-title":"Poster presented at: World Society for Pediatric Infectious Diseases Annual Meeting (WSPID)","author":"Halperin SA"},{"key":"atypb47","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.3.1.77"},{"key":"atypb48","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.8.3.616-623.2001"},{"key":"atypb49","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.vaccine.2008.11.060","volume":"26","author":"Welsch JA","year":"2008","journal-title":"Vaccine"},{"key":"atypb50","volume-title":"Menactra [package insert]","year":"2008"},{"key":"atypb51","doi-asserted-by":"publisher","DOI":"10.1086\/500512"},{"key":"atypb52","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000243215.46312.4a"},{"key":"atypb53","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.07.036"},{"key":"atypb54","volume-title":"Paper presented at: Advisory Committee on Immunization Practices Meeting","author":"Clark T."},{"key":"atypb55","author":"Tucker ME","year":"2009","journal-title":"Pediatric News."},{"key":"atypb56","volume-title":"Paper presented at: European Society for Paediatric Infectious Diseases (ESPID) Annual Meeting","author":"Black S."},{"key":"atypb57","volume-title":"Call to Action: Adolescent Vaccination-Bridging From a Strong Childhood Foundation to a Healthy Adulthood","author":"National Foundation for Infectious Diseases.","year":"2008"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922809354327","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922809354327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:25:26Z","timestamp":1777393526000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0009922809354327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,20]]},"references-count":57,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1177\/0009922809354327"],"URL":"https:\/\/doi.org\/10.1177\/0009922809354327","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,20]]}}}