{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:44:52Z","timestamp":1785329092849,"version":"3.55.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,2,9]],"date-time":"2011-02-09T00:00:00Z","timestamp":1297209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>Brown recluse spider bites may cause severe local and systemic morbidity, but data regarding morbidity in children are limited. This study reviewed inpatient medical records (n = 26; 10 years) with a discharge diagnosis of \u201cspider bite\u201d from a tertiary pediatric hospital. The majority (85%) of children had an inflammatory response accompanying necrosis, usually with signs of secondary cellulitis (77%). Hemolytic anemia (50%), rhabdomyolysis (27%), and acute renal failure (12%) were the most prevalent systemic effects. Hemolytic anemia was bimodal in distribution relative to the time-of-onset of the bite (early, 2.2 \u00b1 0.4; late, 6.9 \u00b1 1.5 days postbite, respectively; P = .004). Although no fatalities occurred in the population, 65% of children had major morbidity, including wound complications requiring surgical care and acute orbital compartment syndrome. The findings emphasize the importance of anticipatory patient\/family education for outpatients and careful monitoring for systemic morbidity in inpatients. Timely and appropriate supportive care should yield favorable outcomes in most cases.<\/jats:p>","DOI":"10.1177\/0009922810388510","type":"journal-article","created":{"date-parts":[[2011,2,9]],"date-time":"2011-02-09T06:16:30Z","timestamp":1297232190000},"page":"252-258","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Complications and Outcomes of Brown Recluse Spider Bites in Children"],"prefix":"10.1177","volume":"50","author":[{"given":"Jonathan J.","family":"Hubbard","sequence":"first","affiliation":[{"name":"Dept. of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura P.","family":"James","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences, Little Rock, AR, USA,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,2,9]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2004.07.012"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-199210000-00008"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(97)70106-9"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2004.71.2.0700239"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(72)80023-4"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041184"},{"key":"atypb7","first-page":"177","volume":"21","author":"Elbahlawan LM","year":"2005","journal-title":"Pediatr Emerg Care"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03340050060033"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00183-4"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0704(05)70059-2"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2007.08.011"},{"key":"atypb12","first-page":"89","volume":"28","author":"Duffey PH","year":"1971","journal-title":"Ariz Med"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.07.021"},{"key":"atypb14","first-page":"423","volume":"135","author":"Escalante-Galindo P.","year":"1999","journal-title":"Gac Med Mex"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1177\/000992287201101113"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1111\/j.0041-1132.2004.04165.x"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/0041-0101(78)90066-1"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(78)90046-2"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12340340"},{"key":"atypb20","first-page":"291","volume":"64","author":"Denny WF","year":"1964","journal-title":"J Lab Clin Med"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(97)70092-1"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198111000-00018"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198511000-00020"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(96)90083-2"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(87)80738-2"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922810388510","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0009922810388510","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:26:32Z","timestamp":1777393592000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0009922810388510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,9]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1177\/0009922810388510"],"URL":"https:\/\/doi.org\/10.1177\/0009922810388510","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,9]]}}}