{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T13:35:51Z","timestamp":1787146551636,"version":"build-2736575974"},"reference-count":35,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>Background. The widespread use of intrapartum antibiotics (IPA) has raised concerns regarding the adverse effects on the newborn. Objectives. To determine if IPA is associated with infantile late-onset serious bacterial infections (SBIs) and with antibiotic resistance. Patients and methods. From 2005 to 2009, data were prospectively collected for all infants born at our center, aged 7 to 90 days, who were hospitalized for fever. Cases included infants with culture-proven SBIs, and controls included infants without SBIs. Results. A total of 71 cases and 124 controls were included. IPA was documented in 11.3% of cases and in 7.3% of controls ( P = .34). Among cases, ampicillin resistance was documented in 85% of antibiotic-exposed infants and in 63% of nonexposed infants ( P = .19). Corresponding rates for first-generation cephalosporin resistance in urinary tract infection were 75% and 23.5% ( P = .04). Conclusion. IPA is associated with a trend toward increased antibiotic resistance in late-onset SBIs. This should be taken into consideration in the selection of empirical therapy for febrile infants.<\/jats:p>","DOI":"10.1177\/0009922811406260","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T19:57:51Z","timestamp":1314907071000},"page":"827-833","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["The Association of Intrapartum Antibiotic Exposure With the Incidence and Antibiotic Resistance of Infantile Late-Onset Serious Bacterial Infections"],"prefix":"10.1177","volume":"50","author":[{"given":"Liat","family":"Ashkenazi-Hoffnung","sequence":"first","affiliation":[{"name":"Schneider Children's Medical Center and Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Melamed","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center and 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