{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:20:10Z","timestamp":1777526410956,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,6,2]],"date-time":"2015-06-02T00:00:00Z","timestamp":1433203200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>Objective: To identify risk factors for antibiotic resistance to Escherichia coli ( E. coli) in children with urinary tract infections (UTIs) in emergency room and primary care clinics. Method: This is a cross-sectional study of children 0 to 18 years of age reported to have E coli\u2013positive UTIs whose medical and laboratory records were systematically reviewed. Result: Compared with girls, boys were 2.29 times (confidence interval [CI] = 1.30-4.02) more likely to have E coli isolates resistant to ampicillin and 2 times more likely (CI = 1.13-3.62) to have isolates resistant to trimethoprim-sulfamethoxazole (TMP\/SMX). Patients with genitourinary abnormalities were 1.57 times more likely to be resistant to ampicillin (CI = 1.03-2.41) and 1.86 times to TMP\/SMX (CI = 1.18-2.94). Conclusion: Higher rates of ampicillin and TMP\/SMX resistant urinary E coli isolates were observed among boys and children with a history of genitourinary abnormality. Age and recent antibiotic prescription are also potential risk factors for resistance.<\/jats:p>","DOI":"10.1177\/0009922815588822","type":"journal-article","created":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T20:14:49Z","timestamp":1433362489000},"page":"19-28","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["First-Line Antimicrobial Resistance Patterns of\n                    <i>Escherichia coli<\/i>\n                    in Children With Urinary Tract Infection in Emergency Department and Primary Care Clinics"],"prefix":"10.1177","volume":"55","author":[{"given":"M. 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